Case report
Postlactational tumoral granulomatous mastitis: A localized immune phenomenon

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Abstract

Recurrent, nodular necrotizing granulomatous mastitis in two patients is reported in detail. Pathologic, immunologic, and bacteriologic studies in one patient indicate that this entity is different from plasmas cell mastitis, fat necrosis, mammary ductal ectasia, and the usual infectious and puerperal mastitis. Systemic antibreast autoimmune mastitis and vasculitis are also ruled out. Its pathogenesis, differential diagnosis, surgical treatment, and prognosis are discussed.

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    Citation Excerpt :

    No patient experienced symptom-onset during lactation. These results are in accordance with previous reports that pregnancy and breastfeeding conditions are associated with an increased risk of IGM15,26,31–34. However, Azlina et al18 and Fletcher et al35 found no association with lactation.

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1

From the Department of Pathology, St. Luke's Hospital, Cleveland, Ohio.

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