On the composition of capillary and venous blood serum
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Capillary blood stability and analytical accuracy of 12 analytes stored in Microtainers®
2023, Practical Laboratory MedicineSkin in the diagnostics game: Wearable biosensor nano- and microsystems for medical diagnostics
2020, Nano TodayCitation Excerpt :These vessels supply blood and nutrients to the other layers of the skin through small capillaries. Significant differences have been found between systemic and capillary blood in the levels of total proteins, bilirubin and certain ions (Ca2+, Na+, Cl−), whereas the concentrations of other analytes such as glucose, urea and K+ are practically identical [24]. As illustrative examples, Table 1 shows a list of selected biomarkers representing ions, metabolites, hormones and proteins classes.
Emergency medical technician-performed point-of-care blood analysis using the capillary blood obtained from skin puncture
2018, American Journal of Emergency MedicineCitation Excerpt :Figs. 3 and 4) The scatter plot for glucose is distributed around the bias line when the average value of glucose is less than approximately 200 mg/dL but becomes more distant from the bias line as the average gets higher (Fig. 4). Although several studies have reported small differences between capillary blood and venous blood analysis using the same laboratory analyzer [12-15], to the best of our knowledge, this is the first study verifying the effectiveness of a POC device using the capillary blood in a clinical setting. The POC analyzer provides increased accessibility and cost-effectiveness in terms of reducing maintenance costs compared with traditional laboratory analyzers, enabling their increased use in the prehospital care setting.
Gene expression profiles are different in venous and capillary blood: Implications for vaccine studies
2016, VaccineCitation Excerpt :A key question is whether the differences we observed, between venous and capillary blood, reflect real biological differences in gene expression between these blood sources, or whether these findings could be explained by sampling artefact. Physiologically, capillary blood is different from venous blood, with different levels of proteins, enzymatic activity and electrolytes, along with different changes after glucose intake, but this does not fully explain the differences seen [18–21]. Several studies have demonstrated that capillary and venous blood have different white blood cell counts, with capillary blood showing a higher leukocyte count than venous blood [22,23].