Heterotransplantation of mixed mesodermal tumor cells in nude mouse—Histology of metastatic foci

doi:10.1016/0090-8258(87)90292-7

Gynecologic Oncology

Volume 27, Issue 2, June 1987, Pages 189-196

https://doi.org/10.1016/0090-8258(87)90292-7 Get rights and content

Abstract

The mixed mesodermal tumor has an admixture of carcinoma and sarcoma. The HIRS-BM tumor cell line, derived from the mixed mesodermal tumor, was transplanted into the peritoneal cavity of BALB/c nude mice, and the metastatic foci were examined histologically and karyologically. The HIRS-BM cells produced mixed mesodermal tumors (admixture of adenocarcinoma and rhabdomyosarcoma) resembling the original tumor. The normal interstitial tissue was not present on the boundary of the sarcoma and carcinoma. These results support the combination theory as the cause of mixed mesodermal tumor.

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Heterotransplantation of mixed mesodermal tumor cells in nude mouse—Histology of metastatic foci

Abstract

Exp. Pathol.

Amer. J. Obstet. Gynecol.

Carcinosarcoma of the uterus, 50-year review of 32 cases (1917–1966)

Obstet. Gynecol.

Establishment and characterization of an estrogen-producing human ovarian granulosa tumor cell line

J. Natl. Cancer Inst.