Cell
ArticleRegulation of embryonic cell adhesion by the cadherin cytoplasmic domain
References (42)
- et al.
The effects of N-cadherin misexpression on morphogenesis in Xenopus embryos
Neuron
(1990) - et al.
Desmoglein shows extensive homology to the cadherin family of cell adhesion molecules
Biochem. Biophy. Res. Commun.
(1990) - et al.
Calcium-dependent cell adhesion molecules
Curr. Opin. Cell Biol.
(1989) Effects of altered expression of the neural cell adhesion molecule, N-CAM, on early neural development in Xenopus embryos
Neuron
(1988)- et al.
Amino acid sequence of bovine muzzle epithelial desmocollin derived from cloned cDNA: a novel subtype of desmosomal cadherins
Differentiation
(1991) - et al.
Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin)
J. Biol. Chem.
(1991) - et al.
Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity
Cell
(1990) - et al.
The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression
Cell
(1991) - et al.
Desmosomal glycoproteins II and III: cadherin-like junctional molecules generated by alternative splicing
J. Biol. Chem.
(1991) - et al.
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
Cell
(1991)
Differential expression of two cadherins in Xenopus laevis
Development
Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells
J. Cell Biol.
Expression of cell adhesion molecule E-cadherin in Xenopus embryos begins at gastrulation and predominates in the ectoderm
J. Cell Biol.
A cadherin-like protein in eggs and cleaving embryos of Xenopus laevis is expressed in oocytes in response to progesterone
J. Cell Biol.
Cloning and sequence analysis of desmosomal glycoprotein-2 and glycoprotein-3 (desmocollins)-cadherin-like desmosomal adhesion molecules with heterogeneous cytoplasmic domains
J. Cell Biol.
Morphoregulatory molecules
Biochemistry
Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein
Ectopic expression of N-cadherin perturbs histogenesis in Xenopus embryos
Development
Expression of a novel cadherin (EP-cadherin) in unfertilized eggs and early Xenopus embryos
Development
Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development
Nature
The uvomorulin-anchorage protein α-catenin is a vinculin homologue
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De Novo Pathogenic Variants in N-cadherin Cause a Syndromic Neurodevelopmental Disorder with Corpus Collosum, Axon, Cardiac, Ocular, and Genital Defects
2019, American Journal of Human GeneticsOn the role of mechanics in driving mesenchymal-to-epithelial transitions
2017, Seminars in Cell and Developmental BiologyCitation Excerpt :This rigid, histology-based identification must be broadened in recognition of the diverse spectrum of functional METs observed in development and homeostasis. The number of studies that directly contradict over-rigid definitions of epithelial and mesenchymal are increasing, including Drosophila mesenchymal cells requiring functional E-cadherin to migrate [107], requirement of N-cadherin for the establishment and functional polarity of the outer epithelium in Xenopus embryos [108], and functionally mesenchymal breast cancer cells that neither downregulate E-cadherin nor express vimentin [109–111]. Instead, METs come in various forms and degrees, ranging from a population of autonomous migratory cells that aggregate and form a structured epithelium or endothelium, to a single independent cell intercalating into an epithelium and adopting the polarity of the surrounding cells, to a cell sheet becoming slightly more polarized.
A Dynamic WNT/β-CATENIN Signaling Environment Leads to WNT-Independent and WNT-Dependent Proliferation of Embryonic Intestinal Progenitor Cells
2016, Stem Cell ReportsCitation Excerpt :Given that βcat-LOF and Lrp5/6-LOF embryos showed similar phenotypes, it is likely that the defects observed are due to perturbations in WNT/β-CATENIN signaling. However, given the important role that β-CATENIN plays in the adherens junctions, we wanted to rule out the possibility that cell-cell adhesion defects are leading to the observed phenotypes (Kintner, 1992; Nagafuchi and Takeichi, 1988; Ozawa et al., 1989, 1990). To do this, we conditionally deleted Cdh1 (Shh-cre;Cdh1-flox/flox;Ecad-LOF), which encodes E-CADHERIN.
Cadherin-based transsynaptic networks in establishing and modifying neural connectivity
2015, Current Topics in Developmental Biology