ORIGINAL ARTICLESIntraepithelial γδ T-cell-receptor lymphocytes and genetic susceptibility to coeliac disease
References (21)
- et al.
Classification of intractable diarrhoea in infancy using clinical and immunohistological criteria
Gastroenterology
(1990) - et al.
Serological markers and HLA genes among healthy first-degree relatives of patients with coeliac disease
Lancet
(1991) - et al.
Subpopulations of human peripheral T gamma/ delta lymphocytes
Immunol Today
(1989) - et al.
Susceptibility to develop celiac disease is primarily associated with HLA DQ alleles
Human Immunol
(1990) - et al.
Dental enamel defects in first-degree relatives of coeliac disease patients
Lancet
(1991) - et al.
Reticulin antibody, arthritis, and coeliac disease in children
Lancet
(1988) - et al.
Expression of disulfide-linked and non-disulfide-linked forms of the T cell receptor gamma/delta heterodimer in human intestinal intraepithelial lymphocytes
Eur J Immunol
(1989) - et al.
Intraepithelial T cells of TCRgamma/delta+CD8- and Vdeltal/Jdeltal+ phenotypes are increased in coeliac disease
Scand J Immunol
(1989) - et al.
Intestinal gamma/delta bearing T lymphocytes in celiac disease and inflammatory bowel diseases in children. Constant increase in celiac disease
Pediatr Res
(1990) - et al.
Increase in gamma/delta T cell receptor bearing lymphocytes in normal small bowel mucosa in coeliac disease
Gut
(1991)
Cited by (119)
Potential selective advantage mechanism for polymorphic genetics in Celiac Disease
2011, Medical HypothesesCitation Excerpt :While many of the HLA variants are associated with a geographical distributions, 90–95% of CD patients express the heterodimer HLA-DQ2 (DQA1∗05/DQB1∗02) which does not follow a geographical distribution pattern [2]. This heterodimer is associated with T Cell changes [3]. This paper suggests a possible etiology and balanced polymorphism found in Celiac Disease and its connection with T Cell irregularities in the mucosa of the gastrointestinal (GI) tract.
Flow cytometry of intestinal intraepithelial lymphocytes in celiac disease
2011, Journal of Immunological MethodsCitation Excerpt :The increase in CD3+ IEL is also the first detectable event during the gluten challenge test. A second abnormality observed in celiac disease is the increase in TcR-γδ+ IEL (Spencer et al., 1989; Holm et al., 1992). Both αβ and γδ IEL proliferate in situ in celiac disease.
Gamma-delta T-cell-mediated dilated cardiomyopathy
2008, International Journal of CardiologyCitation Excerpt :We here describe a case of DCM with heart infiltration by mostly gamma–delta T-cells, who improved significantly by steroid therapy. These gamma–delta T-cells represent about 5% of all T-cells in peripheral blood and lymphoid tissues [1,2], and they are known to be associated with various autoimmune diseases such as celiac diseases [3], rheumatoid arthritis [4], idiopathic polymyositis [5] and Takayasu arteritis [6]. However there has been no report of DCM dominantly mediated by gamma–delta T-cells.
Clinical, Diagnostic and Prognostic Characteristics of Primary Cutaneous Gamma Delta T-cell Lymphomas
2022, Clinical Hematology InternationalResearch progress on pathological mechanism of celiac disease
2022, Medical Journal of Chinese People's Liberation Army