Original article
An important role for chromosome 17, band q25, in the histogenesis of alveolar soft part sarcoma

https://doi.org/10.1016/0165-4608(94)00291-IGet rights and content

Abstract

A cytogenetic study of two cases of alveolar soft part sarcoma showed near-diploid karyotypes with multiple chromosomal rearrangements. An abnormality of the long arm of chromosome 17, involving band q25, is present in both cases and in 2 of 4 cases in the literature. This recurrent structural abnormality probably plays an important role in the histogenesis of this unusual neoplasm and therefore is important for further molecular investigation.

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