Original articleAn investigation into Clostridium perfringens enterotoxin-associated diarrhoea
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Involvement of Bacteria Other Than Clostridium difficile in Antibiotic-Associated Diarrhoea
2016, Trends in MicrobiologyCitation Excerpt :A decreased immune response due to comorbidity or immunosuppressive treatment is a risk factor for C. difficile AAD and may be a risk factor for non-C. difficile AAD since many C. perfringens AAD patients have been identified in oncology and transplant wards [4,30,58,59]. There is also evidence of immunosuppressive treatment prior to disease onset in several cases of S. aureus AAD [11].
Cost-effective screening of pooled faecal specimens from patients with nosocomial diarrhoea for Clostridium perfringens enterotoxin
2011, Indian Journal of Medical MicrobiologyProduction of an antibacterial substance in the digestive tract involved in colonization-resistance against Clostridium perfringens
2010, AnaerobeCitation Excerpt :Type A isolates pre-disposed to produce the C. perfringens enterotoxin (CPE) have become linked to non-food-borne human diseases like antibiotic-associated diarrhoea (AAD) or sporadic non-food-borne diarrhoea (SPOR) [2]. The presence of enterotoxinogenic strains constitutes the highest risk of illness to elderly hospitalized patients [3], and pre-term infants, as recently reported [4]. In 1976, Mitsuoka et al. [5] had shown that 58% of healthy human adults do not harbour C. perfringens in their stools.
Nosocomial and antibiotic-associated diarrhoea caused by organisms other than Clostridium difficile
2009, International Journal of Antimicrobial AgentsEpidemiology of Clostridium species bacteremia in Calgary, Canada, 2000-2006
2008, Journal of InfectionCitation Excerpt :We observed that advancing age and a number of underlying conditions significantly increased the risk for acquiring a clostridial bacteremia. The excess risk in older individuals may not only be related to an increase in co-morbid illnesses but also may be due to an age-related increase of clostridial species in the normal intestinal flora of the elderly.34 While numerous reports have described high rates of malignancy among cohorts of patients with Clostridium species bacteremia, our study is novel in that we quantify the magnitude of increased risk for these infections.4–8
Nosocomial diarrhea caused by Clostridium perfringens in the Tsukuba-Tsuchiura district, Japan
2008, Journal of Infection and Chemotherapy