Special articleTerminology for hepatic allograft rejection☆
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Cited by (163)
Transplantation Pathology
2023, MacSween's Pathology of the Liver, Eighth EditionAcute, Chronic, and Humoral Rejection: Pathologic Features Under Current Immunosuppressive Regimes
2018, Surgical Pathology ClinicsCitation Excerpt :The distinction is clinically important because early chronic rejection is potentially reversible, whereas late stage rejection is generally considered irreversible and usually requires retransplantation. To make an accurate assessment for the degree of ductopenia, 20 or more portal tracts should be assessed, which sometimes requires more than 1 biopsy over time.54 However, there is evidence that ductopenic chronic rejection can be diagnosed reliably by experienced pathologists based on assessment of considerably fewer portal tracts.55
Transplantation Pathology
2018, MacSween's Pathology of the LiverExtracorporeal photopheresis and liver transplantation: Our experience and preliminary data
2017, Transfusion and Apheresis ScienceAntibody-Mediated Rejection After Liver Transplant
2017, Gastroenterology Clinics of North AmericaCitation Excerpt :Both early and late TCMR show the classic histologic features described earlier but the latter also shows central perivenulitis with associated necrosis, less bile duct injury, and a more homogeneous inflammatory infiltrate of histiocytes, lymphocytes, and plasma cells with mild interface activity.17,24 AMR is caused by preformed antidonor antibodies, ABO incompatibilities, or de-novo antibodies that develop after transplant.27–31 Preformed antidonor antibodies either bind to ABO antigens or to HLA class I and class II antigens expressed on endothelial cells.
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Prepared by a panel of an International Working Party on the Terminology of Chronic Hepatitis, Hepatic Allograft Rejection, and Nodular Lesions of the Liver. The working party was organized and funded by the World Congresses of Gastroenterology, Los Angeles, 1994. (Program Chair: Douglas B. McGill, MD) The material was presented in part at that meeting. See appendix for a list of panel members.