Immunohistochemical evaluation and in situ hybridization in a case of oral inverted ductal papilloma

Journal of Oral and Maxillofacial Surgery

Volume 52, Issue 5, May 1994, Pages 503-506

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There are more references available in the full text version of this article.

Diagnostic Pathology: Head & Neck
2017, Diagnostic Pathology: Head and Neck
Buccal mass excreting pus-like material
2015, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Inverted ductal papilloma arising from the buccal minor salivary gland: A case report and immunohistochemical study
2012, Oral Science International
Citation Excerpt :
HPV types 6 and 11 were identified in 33.3% of these 9 cases of oral IDP [4,12,16,20]. Further studies are needed to determine the viral implications involved in the pathogenesis of this lesion [16]. IDP exhibits nonaggressive biologic behavior.
Oral inverted ductal papilloma is a rare, benign epithelial tumor that exhibits an endophytic growth pattern and is found almost exclusively in the minor salivary glands. We report on a case of inverted ductal papilloma in the buccal mucosa. We also performed an immunohistochemical study. The tumor cells were positive for cytokeratin and epithelial membrane antigen, while negative for calponin, S-100 protein, α-SMA, vimentin, and desmin. This result indicated that the lesion arises from the excretory duct near the oral mucosal surface but not the myoepithelial cells. In addition, Ki-67 labeling index of 3.96% indicated the low level of proliferation.
Salivary glands
2009, Modern Surgical Pathology
Salivary and lacrimal glands
2009, Diagnostic Surgical Pathology of the Head and Neck: Expert Consult - Online and Print
Salivary Glands
2009, Modern Surgical Pathology

^∗: Clinical Assistant Professor, Division of Oral Pathology, School of Dentistry, University of Minnesota, Minneapolis, MN.

^†: Associate Professor, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.