Liver transplantationCauses of retransplantation after primary liver transplantation in 4000 consecutive patients: 2 to 19 years follow-up
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Results
In the follow-up period 774 patients (19.4%) received a second transplant, 148 (3.7%) received a third transplant, 20 (0.5%) received a fourth transplant, and five patients (0.13%) received more than four allografts. The rate of retransplantation and the causes of retransplantation in various eras are shown in Table 1, Table 2. The overall rate of retransplantation has declined significantly in each subsequent era: from 33.4% in era A to 23.7% in era B and 13.4% in era C. (P = .001). This may
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Cited by (65)
Liver Retransplantation: How Much Is Too Much?
2017, Clinics in Liver DiseaseCitation Excerpt :In several studies, there are now fewer retransplants for acute and chronic rejection and less for ischemic complications and disease recurrence, but PNF rates have remained about the same.5,9 Rates for hepatic arterial thrombosis (HAT), as reported by Kashyap and colleagues,9 decreased over 17 years from 8.1% to 3.7%, but Pfitzmann and colleagues5 reported that retransplant rates for HAT increased in their population, possibly because of the use of more marginal liver donors and performing transplants in sicker patients. There is also a shift away from attempting to manage early HAT expectantly with management of biliary complications toward early retransplantation.
Irreversible graft failure requiring 3 repeated liver transplantations combined with a 2-stage liver transplantation: A case report
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2015, Transplantation of the Liver: Third EditionLiver retransplantation in adults: A 20-year experience of one center in southern Brazil
2013, Annals of HepatologyCitation Excerpt :Thus, primary dysfunction/nonfunction is one of the major causes of early LReTx,12,13 which has then been viewed as an ethically required practice. Late LReTx, occurring months or years after the initial transplant, is usually performed for recurrent disease, late technical problems, and more rarely, chronic rejection.14. –16 Recurrence of primary disease in the graft, especially hepatitis C virus (HCV) infection, has become the most common indication for late LReTx.12,14,16
VI consensus document by the Spanish Liver Transplantation Society
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