Research ReportBiliary adenocarcinoma: Characterisation of three new human tumor cell lines*
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2019, iScienceCitation Excerpt :A panel of 22 BTC cell lines derived from tumors from distinct anatomical locations within the biliary tree was assembled from international cell repositories and individual investigators (Table S1). The panel comprised the majority of BTC lines described in the literature (Homma et al., 1987, 1988; Knuth et al., 1985; Koyama et al., 1980; Ku et al., 2002; Kusaka et al., 1988; Miyagiwa et al., 1989; Yamada et al., 1997), including two cell lines, KKU-M055 and KKU-M213, derived from liver-fluke-associated intrahepatic cholangiocarcinoma (Obchoei et al., 2011; Tepsiri et al., 2005). The total number of mutations (SNVs + InDels) ranged from 315 to 623 (mean 394) across the cell lines (Figures 1A–1C and Table S2).
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This work was supported by grants from the Deutsche Forschungsgemeinschaft Kn-180/3, Di-245/3 and Sonderforschungsbereich 107.