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REFERENCES
Wilmot FC, and Robertson GW: Senecio disease, or cirrhosis of the liver due to senecio poisoning. Lancet, 2:848–849, 1920.
Bras G, Jeliff DB, Stuart KL: Veno-occlusive disease of the liver with non-portal type of cirrhosis occuring in Jamaica. Arch Pathol, 57:285–300, 1954
Schulman H, Gown AM, Nugent M: Hepatic veno-occlusive disease after bone marrowtransplantation-immunohistochemical identification of the material within occluded central venules. Am J Pathol 127:549–558, 1987
Liano F, Moreno A, Matesanz R, Teruel JL, Redondo C, Garcia-Martin F, Orte L, Ortuno J: Veno-occlusive hepatic disease of the liver in renal transplantation is azathioprine the cause? Nephron, 51:509–516, 1989
Bearman SI, et al: Treatment of hepatic venocclusive disease with recombinant human tissue plasminogen activator and heparin in 42 marrow transplant patients. Blood 89:1501–1516, 1997
Richardson PG, et al: Treatment of severe veno-occlusive disease with defibrotide: compassionate use results in response without significant toxicity in a high-risk population. Blood 92:737–744, 1998
DeLeve LD, et al: Toxicity of azathioprine and monocrotaline in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease. Hepatology, 23:589–599, 1996.
Russmann S, et al: Veno-occlusive disease, nodular regenerative hyperplasia and hepatocellular carcinoma after azathioprine treatment in a patient with ulcerative colitis. Eur J Gastroenterol Hepatol13:287–290, 2001
Boehme MWJ, et al: Elevated serum levels and reduced immunhistochemical Expression of thrombomodulin in active ulcerative colitis. Gastroenterology 113:107–117, 1997
Stevens TR, et al: Anti-endothelial cell antibodies in inflammatory bowel disease. Dig Dis Sci 38:426–432, 1993
Holtmann M, Schütz M, Galle PR, Neurath MF: Functional relevance of soluble and transmembrane TNF and TNF-signal transduction in gastrointestinal diseases with special reference to inflammatory bowel diseases (submitted)
Levi M, et al: Pathogenesis of disseminated intravascular coagulation in sepsis. JAMA 270(8): 975–979, 1993
Koenings KP, McPhedran P, Spiro HM:Thrombosis in inflammatory bowel disease. J Clin Gastroenterol 9:617–621, 1987
Talbot RW, et al: Vascular complications of inflammatory bowel disease. Mayo Clin Proc 61:140–145, 1986
Levy PJ, Tabares AH, Olin JW: Lower extremity arterial occlusions in young patients with Crohn's colitis and premature atherosclerosis: report of six cases. AmJ Gastroenterol 92:494–497,1997
Liebman HA, et al: The factor V Leiden mutation increases the risk of venous thrombosis in patients with inflammatory bowel disease. Gastroenterology, 115:830–834, 1998
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Holtmann, M., Schreiner, O., Köhler, H. et al. CASE REPORT: Veno-Occlusive Disease (VOD) in Crohn's Disease (CD) Treated with Azathioprine. Dig Dis Sci 48, 1503–1505 (2003). https://doi.org/10.1023/A:1024755521423
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DOI: https://doi.org/10.1023/A:1024755521423