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Maternal Floor Infarction of the Placenta: Association With Central Nervous System Injury and Adverse Neurodevelopmental Outcome

Journal of Perinatology volume 22, pages 236–241 (2002)Cite this article

Abstract

OBJECTIVE: To compare cranial ultrasound studies and neurodevelopmental outcome of preterm infants affected by maternal floor infarction (MFI) of the placenta to gestational age-matched controls over an 8-year period from a single institution.

STUDY DESIGN: Retrospective case/control study.

RESULTS: Compared to gestational age-matched controls, infants born to mothers with MFI had a higher incidence of CNS injury on neonatal cranial ultrasound examinations and at follow-up were more likely to have a suspicious or abnormal neurologic examination. MFI cases had lower developmental scores in all areas tested and were more likely to have neurodevelopmental impairment.

CONCLUSION: Infants born to mothers with MFI should have serial neonatal cranial ultrasound examinations to detect CNS injury and neurodevelopmental assessment during early childhood.

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Authors and Affiliations

  1. Departments of Pediatrics/Division of Neonatology, Pathology and Reproductive Medicine, University of California at San Diego, San Diego, CA, USA

    Ira Adams-Chapman MD, Yvonne E Vaucher MPH, MD, Raul F Bejar MD, Kurt Benirschke MD, Rebecca N Baergen MD & Thomas R Moore MD

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  1. Ira Adams-Chapman MD
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  2. Yvonne E Vaucher MPH, MD
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  3. Raul F Bejar MD
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  4. Kurt Benirschke MD
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  5. Rebecca N Baergen MD
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  6. Thomas R Moore MD
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Adams-Chapman, I., Vaucher, Y., Bejar, R. et al. Maternal Floor Infarction of the Placenta: Association With Central Nervous System Injury and Adverse Neurodevelopmental Outcome. J Perinatol 22, 236–241 (2002). https://doi.org/10.1038/sj.jp.7210685

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