Elsevier

Placenta

Volume 22, Issue 5, May 2001, Pages 399-404
Placenta

Regular Articles
Weights of Placentae From Small-for-Gestational Age Infants Revisited

https://doi.org/10.1053/plac.2001.0630Get rights and content

Abstract

The objective of the study was to investigate the association between placental weight and birthweight in appropriate (AGA) and small for gestational age (SGA) infants. Placental weight, birthweight and their ratio in chromosomally normal singleton pregnancies with SGA (n=1569) and AGA (n=15 047) infants were compared, and their determinants were studied by logistic regression. SGA infants had 24 per cent smaller placentae than AGA infants when gestational age was used as a covariate. Placental actual weight was also lower in SGA infants than in AGA infants of the same birthweight (P< 0.001). SGA infants had smaller placentae than the controls, suggesting that fetal growth depends on the actual weight of the placenta. Future studies should evaluate whether growth restriction could be reversed by therapeutic approaches increasing placental weight.

References (22)

  • MD Kilby et al.

    Localisation of HGF and its receptor (c-met) protein and mRNA in human term placenta

    Growth Factors

    (1996)
  • Cited by (150)

    • Abnormalities of Fetal Growth

      2023, Avery's Diseases of the Newborn
    View all citing articles on Scopus
    f1

    To whom correspondence should be addressed: Dept. of Obstetrics and Gynecology, Kuopio University Hospital, 70211 Kuopio, Finland. Fax: 358 17 172486; E-mail:[email protected]

    View full text