Original ArticleRadial scar and carcinoma of the breast: microscopic findings in 32 cases
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Cited by (38)
Radial scar of the breast: Is it possible to avoid surgery?
2017, European Journal of Surgical OncologyCitation Excerpt :The clinical management of RS is currently controversial. Although a recent study demonstrated that there is no evidence to suggest that RS, even larger than 10 mm, have any greater risk of developing cancer after excision than the general population,16 a significant number of observations show the opposite and conclude that there are a possible association with malignancy.8,17–22 The reason for this association remains uncertain.
Surgical excision outcome after radial scar without atypical proliferative lesion on breast core needle biopsy: A single institutional analysis
2016, Annals of Diagnostic PathologyCitation Excerpt :The radiologic appearance of RS overlaps that of invasive carcinoma (IC), and it poses a challenge to radiologists [3-6]. RS has been found to be associated with both benign proliferative lesions and atypical/malignant proliferative lesions [7-12]. The management of patients with RS detected on image-guided core needle biopsies (CNBs) is still a matter of debate because the data from previous studies are conflicting in regard to whether these lesions are independent risk factors for malignancy [7-30].
Pathologic findings of follow-up surgical excision for radial scar on breast core needle biopsy
2016, Human PathologyCitation Excerpt :RS has been associated with both benign proliferative lesions (usually ductal hyperplasia) and atypical/malignant lesions with broad and overlapping ranges of frequency [3–8]. Although various studies have investigated the association between RS and breast cancers, data from the literature are still conflicting in regard to whether these lesions are independent risk factors for malignancy or a marker of higher risk [3–26]. Some studies also investigated whether surgical excision is necessary for patients with RS identified on CNB and attributed the associated risk to accompanying proliferative lesions, especially those with atypia [12,13,15,16].
Long term follow-up and risk of breast cancer after a radial scar or complex sclerosing lesion has been identified in a benign open breast biopsy
2011, European Journal of Surgical OncologyCitation Excerpt :The main clinical significance of radial scars is their possible association with the development of breast cancer. Several observations have led to this suggestion including similar mammographic and histological appearances3–7; the finding of carcinomas in radial scars1,5,8–16; and the association with other forms of benign proliferative disease known to predispose to the development of breast cancer.17–20 Various studies have investigated the possible association between radial scars and breast cancer, with conflicting results.
Therapeutic mammotome excisions: Radial scars
2008, Breast Cancer OnlineImaging and Management of Radial Scars and Complex Sclerosing Lesions
2023, Radiographics