Original ArticlesAssessment of complications of EUS-guided fine-needle aspiration☆,☆☆
Section snippets
Patients and methods
From January 1998 to October 1999, 322 consecutive patients underwent EUS-FNA to establish a diagnosis for lesions involving, or adjacent to, the upper or lower GI tract. These included suspected upper or lower GI tract, pancreatic, liver, pelvic and mediastinal malignancies. EUS-FNA was also performed to confirm diagnoses in patients with cystic pancreatic lesions, tuberculous lymphadenopathy, and other benign disorders. The procedures were performed in 2 centers by 3 experienced
Results
The patient population included 322 patients (171 men) with a mean age of 59.5 years. EUS-FNA was performed in a total of 345 lesions and required a mean of 2.1 passes per lesion (± 1.0). The overall complication rate was 1.6% (5 of 322 patients). There was no death and no patient required surgery.
The pancreas was the most frequent site of EUS-FNA and was aspirated in 248 (72%) cases. Antibiotics were given prophylactically in 66% of cases before aspiration of pancreatic cysts. Of the
Discussion
EUS-FNA is an accurate technique for differentiating benign and malignant lesions of the pancreas, lymph nodes, and those adjacent to the upper and lower GI tract wall.6, 7, 9, 10, 11, 12 Although it has been suggested that complication rates are greater in patients undergoing EUS-FNA compared with standard upper endoscopy, diagnostic EUS, or percutaneous FNA,11 the exact complication rate for this procedure remains poorly defined.
The overall complication rate in this study was 1.5%, which is
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Reprint requests: Dermot O'Toole, MD, Service de Gastroentérologie, Hôpital Beaujon, 100, boulevard du Général Leclerc, F-92118 Clichy Cedex, France.
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Gastrointest Endosc 2001;53:470-4