ReportsBasaloid/follicular hyperplasia overlying connective tissue/mesenchymal hamartomas simulating basal cell carcinomas☆,☆☆,★,★★
Section snippets
Material and methods
Three patients had lesions that had been present for decades (Table I).
Ant, Anterior; F, female; M, male; W, white.Patient No. Age (y)/Sex/Race Location Size (cm) Duration (y) 1 71/F/W Left lateral ant low leg 3 >40 2 80/F/W Right forehead 5 × 6 40-50 3 42/F/W Right ant chest 4 × 5 cm >30
Discussion
We are not aware of any previous reports of basaloid hyperplasia overlying connective tissue/mesenchymal hamartomas. We believe that these hamartomas are distinct from NS and dermatofibromas with areas of basaloid hyperplasia. NS has been associated with multiple ectodermal and mesodermal malformations including other cutaneous hamartomas.2 However, unlike most reports of NS, the lesions in this report were not noticed until later in life, and they did not become verrucous. Only case 1 showed a
References (12)
- et al.
Immunohistochemical nuclear staining for p53, PCNA, and Ki-67 in different histologic variant of basal cell carcinoma
J Am Acad Dermatol
(1997) - et al.
Nevus sebaceus: a report of 140 cases with special regard to the development of secondary malignant tumors
Br J Dermatol
(1970) - et al.
Nevus sebaceus of Jadassohn: part of a new neurocutaneous syndrome?
Arch Dermatol
(1968) - et al.
Follicular basal cell hyperplasia overlying dermatofibroma
Am J Surg Pathol
(1997) - et al.
Immunohistochemical detection of p53 in epidermal proliferations overlying dermatofibromas
Acta Derm Venereol
(1995) - et al.
Ber-EP4 immunoreactivity in normal skin and cutaneous neoplasms
Mod Pathol
(1995)
Cited by (0)
- ☆
The opinions or assertions herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Navy, the Department of the Army, or the Department of Defense.
- ☆☆
Reprints not available from authors.
- ★
*Drs Skelton and Smith are now with Dermatopathology, Departments of Dermatology and Pathology, University of Alabama at Birmingham.
- ★★
**Dr Corbett is now practicing in Wilson, North Carolina.