Chest
Volume 103, Issue 5, May 1993, Pages 1621-1623
Journal home page for Chest

Selected Reports
Bronchiolitis Obliterans Organizing Pneumonia: An Unusual Cause of Solitary Pulmonary Nodule

https://doi.org/10.1378/chest.103.5.1621Get rights and content

Bronchiolitis obliterans organizing pneumonia (BOOP) is a pulmonary disorder with a wide spectrum of radiologic features. Usually, these are bilateral, patchy, alveolar, or ground-glass infiltrates, but other presentations have also been described. We present a case in which the radiologic appearance was a cavitated pulmonary solitary nodule. We think that this finding may justify the inclusion of BOOP in the differential diagnosis of the pulmonary solitary nodule.

Section snippets

CASE REPORT

The patient was a 54-year-old man, 80 pack-year smoker. He was working for a heating factory with mild exposure to copper fumes, hydrochloric acid, and sodium hydroxide. He was a usual cougher.

In the month prior to the hospital admission, he began a progressive nocturnal cough with production of sputa initially rusty and finally hemoptoic. He also suffered from malaise, asthenia, anorexia, and pleuritic, right flank pain without fever. Physical findings were absolutely unremarkable when he was

DISCISSION

In 1983, Epler and coworkers,6 recognizing the diversity of the causes of bronchiolitis obliterans (BO), proposed the following clinical classification: (1) secondary to toxic fumes; (2) after infectious diseases; (3) associated with connective tissue processes; (4) secondary to localized lesions; and (5) idiopathic BOOP. Soon after, they better described BOOP as a subset of patients with BO without apparent cause or associated diseases, a pathologically well-defined pattern, and a good

REFERENCES (9)

There are more references available in the full text version of this article.

Cited by (38)

  • Pathology-radiology correlation of common and uncommon computed tomographic patterns of organizing pneumonia

    2018, Human Pathology
    Citation Excerpt :

    Approximately 50% of nodular OP lesions contain air bronchograms, pleural tags, pleural or interlobular septal thickening, and parenchymal bands. The differential diagnosis includes lymphoma, multicentric adenocarcinoma, and invasive fungal infection in immunocompromised patients [23,24]. Perilobular thickening outlines affected pulmonary lobules, often with peripheral arcade-like polygonal opacities (Fig. 15A), correlating with accumulation of organizing exudate in the peripheral lobular alveoli with or without interlobular septal thickening [25].

  • Prognostic value of clinical, morphologic, and immunohistochemical factors in patients with bronchiolitis obliterans-organizing pneumonia

    2013, Human Pathology
    Citation Excerpt :

    True hybrid cases of either BOOP and chronic eosinophilic pneumonia or BOOP and hypersensitivity pneumonitis have been described [15,16]. Focal pneumonias, especially those cases as a consequence of an aspiration [17-19], may be indistinguishable from BOOP, particularly if it affects the apicoposterior segment of the upper lobe [20]. Only the presence of definite foreign body reaction may help with the differential diagnosis [8].

  • Cryptogenic organising pneumonia

    2005, Revue de Pneumologie Clinique
View all citing articles on Scopus
View full text