Elsevier

Pathology

Volume 25, Issue 4, 1993, Pages 420-422
Pathology

Pancreatic cytology and adenosquamous carcinoma of the pancreas

https://doi.org/10.3109/00313029309090873Get rights and content

Summary

Primary carcinoma of the pancreas exhibiting squamous differentiation is unusual. We present such a case which was diagnosed by percutaneous fine needle aspiration biopsy. A cytological diagnosis of squamous cell carcinoma lead to the question: was the tumour primary or secondary? Subsequent post-mortem examination confirmed a primary carcinoma of the head of the pancreas with predominantly squamous differentiation and a small component of glandular differentiation. Cytologic diagnosis of squamous cell carcinoma should prompt a review of clinical and radiologic data. Evidence of a malignant glandular component should also be sought.

References (13)

  • L.L. Fajardo et al.

    Computed tomography findings in squamous cell carcinoma of the pancreas

    CT: J Comput Tomogr

    (1988)
  • J. Chen et al.

    Morphological study of 391 cases of exocrine pancreatic tumors with special reference to the classification of exocrine pancreatic carcinoma

    J Pathol

    (1985)
  • A.L. Cubilla et al.

    Tumors of the exocrine pancreas

    (1984)
  • T. Morohoshi et al.

    Exocrine pancreatic tumours and their histological classification: A study based on 167 autopsy and 97 surgical cases

    Histopathology

    (1983)
  • R. Kolbusz et al.

    Asymptomatic esophageal squamous cell carcinoma masquerading as a rare primary pancreatic carcinoma

    Acta Cytol

    (1988)
  • R.W. Cihak et al.

    Acanthoma (adenosquamous carcinoma) of the pancreas

    Cancer

    (1972)
There are more references available in the full text version of this article.

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  • Squamous Cell Carcinoma of the Pancreas

    1999, Journal of Gastrointestinal Surgery
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