Abstract
Cancer-screening tests for internal organs are severely constrained by low specificity or sensitivity, cost, and morbidity. We report a non-invasive immunofluorometric assay for detection of urothelial cancers based on ectopic expression of the DNA replication protein Mcm5.
MeSH terms
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Biomarkers, Tumor
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Carcinoma, Transitional Cell / pathology*
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Cell Cycle Proteins / urine*
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Fluorescent Antibody Technique, Indirect*
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Humans
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Sensitivity and Specificity
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Urinary Bladder Neoplasms / pathology*
Substances
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Biomarkers, Tumor
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Cell Cycle Proteins
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MCM5 protein, human