Clear cell papulosis is a newly described entity first described in 1987. The disease, characterized clinically by multiple small whitish maculopapular lesions, shows scattered clear cells within the basal keratinocytes that are immunoreactive for antibodies against cytokeratin, carcinoembryonic antigen, epithelial membrane antigen, and gross cystic fluid protein-15 on histologic examination. To date, only 10 cases have been reported; all were young children below the age of 4 years. We report a case of clear cell papulosis in a 46-year-old Indian woman.
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