Abstract
Tumors contain a subpopulation of tumor-propagating cells (TPCs) that are critical for their growth. In this issue, Read, Wechsler-Reya, and colleagues show that in an animal model of medulloblastoma, TPCs express the surface marker CD15 and have properties distinct from neural stem cells.
MeSH terms
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Animals
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Antigens, Neoplasm / metabolism
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Cerebellar Neoplasms* / pathology
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Cerebellar Neoplasms* / physiopathology
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Humans
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Lewis X Antigen / metabolism
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Medulloblastoma* / pathology
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Medulloblastoma* / physiopathology
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Mice
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Neoplastic Stem Cells* / pathology
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Neoplastic Stem Cells* / physiology
Substances
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Antigens, Neoplasm
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Lewis X Antigen