Perivascular epithelioid cell tumors (PEComas) harboring TFE3 gene rearrangements lack the TSC2 alterations characteristic of conventional PEComas: further evidence for a biological distinction

Am J Surg Pathol. 2012 May;36(5):783-4. doi: 10.1097/PAS.0b013e31824a8a37.
No abstract available

Publication types

  • Letter

MeSH terms

  • Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / genetics*
  • Biomarkers, Tumor / metabolism
  • Gene Fusion*
  • Genetic Markers
  • Humans
  • Loss of Heterozygosity*
  • Perivascular Epithelioid Cell Neoplasms / genetics*
  • Perivascular Epithelioid Cell Neoplasms / metabolism
  • Perivascular Epithelioid Cell Neoplasms / pathology
  • Tuberous Sclerosis Complex 2 Protein
  • Tumor Suppressor Proteins / genetics*
  • Tumor Suppressor Proteins / metabolism

Substances

  • Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
  • Biomarkers, Tumor
  • Genetic Markers
  • TFE3 protein, human
  • TSC2 protein, human
  • Tuberous Sclerosis Complex 2 Protein
  • Tumor Suppressor Proteins