Neuroleptic malignant syndrome and malignant hyperthermia. Important issues for the medical consultant

Med Clin North Am. 1993 Mar;77(2):477-92. doi: 10.1016/s0025-7125(16)30265-6.

Abstract

Neuroleptic malignant syndrome and malignant hyperthermia share two cardinal clinical features: hypothermia and rigidity. Both syndromes can result in rhabdomyolysis and have high mortality rates if left untreated. This article reviews each syndrome and its pathogenesis and treatment.

Publication types

  • Review

MeSH terms

  • Dantrolene / therapeutic use
  • Diagnosis, Differential
  • Dopamine Agents / therapeutic use
  • Humans
  • Malignant Hyperthermia* / diagnosis
  • Malignant Hyperthermia* / drug therapy
  • Malignant Hyperthermia* / etiology
  • Neuroleptic Malignant Syndrome* / diagnosis
  • Neuroleptic Malignant Syndrome* / drug therapy
  • Neuroleptic Malignant Syndrome* / etiology
  • Referral and Consultation

Substances

  • Dopamine Agents
  • Dantrolene