Leiomyosarcoma of the bladder eighteen years after cyclophosphamide therapy for retinoblastoma

Urol Int. 1993;51(1):49-53. doi: 10.1159/000282511.

Abstract

We report a case of leiomyosarcoma in the bladder which occurred in an 18-year-old boy who had been treated with cyclophosphamide over a period of 6 years for retinoblastoma diagnosed 50 days postpartum. Total cystectomy and formation of an ileal conduit were performed. Three years after the operation, he was tumor-free.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cyclophosphamide / therapeutic use*
  • Cystectomy
  • Eye Neoplasms / drug therapy*
  • Humans
  • Leiomyosarcoma / diagnosis
  • Leiomyosarcoma / epidemiology*
  • Leiomyosarcoma / therapy
  • Male
  • Retinoblastoma / drug therapy*
  • Time Factors
  • Urinary Bladder / pathology
  • Urinary Bladder Neoplasms / diagnosis
  • Urinary Bladder Neoplasms / epidemiology*
  • Urinary Bladder Neoplasms / therapy

Substances

  • Cyclophosphamide