Abstract
A case of infiltrating carcinoma of the breast with features similar to those seen in acinic cell carcinoma of the parotid gland is described in a 42-year-old woman. The neoplastic cells were immunoreactive with anti-lysozyme- and anti-salivary-type amylase antisera and contained electron-dense cytoplasmic globules similar to those seen in acinic cell carcinoma of salivary glands. One lymph node out of 18 was found to contain a metastatic deposit. The patient is alive and well 1 year after mastectomy. This appears to be the first case of carcinoma with acinic cell-like features reported in the breast.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Amylases / analysis
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Amylases / immunology
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Breast Neoplasms / chemistry
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Breast Neoplasms / pathology*
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Breast Neoplasms / ultrastructure
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Carcinoma, Acinar Cell / chemistry
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Carcinoma, Acinar Cell / pathology*
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Carcinoma, Acinar Cell / ultrastructure
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Female
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Humans
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Immune Sera / analysis
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Immune Sera / immunology
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Immunohistochemistry
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Lymph Nodes / pathology
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Microscopy, Electron
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Muramidase / analysis
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Muramidase / immunology
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Parotid Neoplasms / chemistry
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Parotid Neoplasms / pathology
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Parotid Neoplasms / ultrastructure
Substances
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Immune Sera
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Amylases
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Muramidase