Eikenella corrodens is a slow-growing, facultative, anaerobic, gram-negative bacillus that is part of the normal oral flora and is found in dental plaque. It has become increasingly recognized as a pathogen in nonimmunocompromised and immunocompromised hosts. A case of a submandibular abscess due to Eikenella corrodens, which was successfully treated by administration of cefuroxime accompanied by incision and drainage, is presented. Dermatologists need to be aware of this pathogen is the evaluation of suppurative lesions of the head and neck.