We describe an interesting case of uterine stromal nodule with sex-cord-like differentiation of retiform type. The tumour occurred in a 51-year-old woman. It contained areas of retiform patterns mimicking an epithelial component of some of mullerian biphasic tumours. Areas of classical sex-cord-like and smooth muscle differentiations were also found. The sex-cord-like cells revealed a smooth muscle phenotype in ultrastructural and immunohistochemical studies.