Laboratory interpretative comments and guidance: clinical and operative outcomes on moderate to severe hyponatraemia patient management

J Clin Pathol. 2023 Feb;76(2):116-120. doi: 10.1136/jclinpath-2021-207611. Epub 2021 Sep 13.

Abstract

Aims: Hyponatraemia is the most common body fluid disorders but often goes unnoticed. Our laboratory incorporated a standardised procedure to help clinicians detect moderate/severe hyponatraemia. The study aims were to evaluate the outcomes on patient care and clinicians' satisfaction.

Methods: The study, observational and retrospective, included 1839 cases, adult and paediatric patients, with sodium concentration <130 mmol/L. The procedure consisted of interpretative comments in the emergency and core laboratories report and the point-of-care testing blood gas network report. We evaluated hyponatraemia length in two equal periods: before and after the implementation. We conducted a survey addressed to the staff of the clinical settings involved to know their satisfaction.

Results: The median hyponatraemia length decreased significantly from 4.95 hours (2.08-16.57) in the first period to 2.17 hours (1.06-5.39) in the second period. The lack of hyponatraemia patients follow-up was significantly less after the procedure implementation. The survey was answered by 92 (60 senior specialists and 32 residents) out of 110 clinicians surveyed. Ninety of them (98%) answered positively.

Conclusions: We have demonstrated the reduction in the time for diagnosing and management by physicians, the higher uniformity in the time required to solve hyponatraemia episodes following our laboratory procedure and the clinicians' satisfaction.

Keywords: automation; biochemistry; electrolytes; healthcare; point-of-care testing; quality assurance.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Child
  • Humans
  • Hyponatremia* / diagnosis
  • Hyponatremia* / therapy
  • Laboratories
  • Retrospective Studies
  • Sodium

Substances

  • Sodium