The complete sequence of a human genome

S Nurk, S Koren, A Rhie, M Rautiainen, AV Bzikadze… - Science, 2022 - science.org
Since its initial release in 2000, the human reference genome has covered only the
euchromatic fraction of the genome, leaving important heterochromatic regions unfinished …

The ENCODE (ENCyclopedia of DNA elements) project

EA Feingold, PJ Good, MS Guyer, S Kamholz… - Science, 2004 - scholarworks.bwise.kr
The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional
elements in the human genome sequence. The pilot phase of the Project is focused on a …

Topographical and temporal diversity of the human skin microbiome

EA Grice, HH Kong, S Conlan, CB Deming, J Davis… - science, 2009 - science.org
Human skin is a large, heterogeneous organ that protects the body from pathogens while
sustaining microorganisms that influence human health and disease. Our analysis of 16 S …

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

LA Matsuda, SJ Lolait, MJ Brownstein, AC Young… - Nature, 1990 - nature.com
MARIJUANA and many of its constituent cannabinoids influence the central nervous system
(CNS) in a complex and dose-dependent manner1, 2. Although CNS depression and …

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

DS Gerhard, L Wagner, EA Feingold… - Genome …, 2004 - europepmc.org
Abstract The National Institutes of Health's Mammalian Gene Collection (MGC) project was
designed to generate and sequence a publicly accessible cDNA resource containing a …

Comparative analyses of multi-species sequences from targeted genomic regions

JW Thomas, JW Touchman, RW Blakesley… - Nature, 2003 - nature.com
The systematic comparison of genomic sequences from different organisms represents a
central focus of contemporary genome analysis. Comparative analyses of vertebrate …

A diversity profile of the human skin microbiota

EA Grice, HH Kong, G Renaud, AC Young… - Genome …, 2008 - genome.cshlp.org
The many layers and structures of the skin serve as elaborate hosts to microbes, including a
diversity of commensal and pathogenic bacteria that contribute to both human health and …

Gelcasting of alumina

AC Young, OO Omatete, MA Janney… - Journal of the …, 1991 - Wiley Online Library
Gelcasting is a novel method for molding ceramic powder based on a synthesis of concepts
derived from traditional ceramics and polymer chemistry. Gelcasting of alumina is described …

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

TI Bonner, AC Young, MR Bran, NJ Buckley - Neuron, 1988 - cell.com
The human and rat genes for a fifth muscarinic receptor have been cloned and expressed in
mammalian ceils. The 532 amino acid human protein has 89% sequence identity to the 531 …

Identification of a family of muscarinic acetylcholine receptor genes

TI Bonner, NJ Buckley, AC Young, MR Brann - Science, 1987 - science.org
Complementary DNAs for three different muscarinic acetylcholine receptors were isolated
from a rat cerebral cortex library, and the cloned receptors were expressed in mammalian …