Frequency and spectrum of cancers in the Peutz-Jeghers syndrome

N Hearle, V Schumacher, FH Menko, S Olschwang… - Clinical Cancer …, 2006 - AACR
Background: Although an increased cancer risk in Peutz-Jeghers syndrome is established,
data on the spectrum of tumors associated with the disease and the influence of germ-line …

Upper gastrointestinal cancer in patients with familial adenomatous polyposis

AD Spigelman, IC Talbot, CB Williams, P Domizio… - The Lancet, 1989 - Elsevier
Abstract 102 patients with familial adenomatous polyposis underwent upper gastrointestinal
endoscopy as a screening test for gastroduodenal adenomas. 100 had duodenal …

Adverse events in surgical patients in Australia

AK Kable, RW Gibberd… - International Journal for …, 2002 - academic.oup.com
Objective. To determine the adverse event (AE) rate for surgical patients in Australia.
Design. A two-stage retrospective medical record review was conducted to determine the …

Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis

KP Nugent, KCR Farmer, AD Spigelman… - Journal of British …, 1993 - academic.oup.com
Twenty-four patients with familial adenomatous polyposis who had previously undergone
prophylactic colectomy and had advanced duodenal polyposis were entered into a …

Clinical governance: a review of key concepts in the literature

JF Travaglia, D Debono, AD Spigelman… - … An International Journal, 2011 - emerald.com
The authors reviewed and analysed published clinical governance abstracts from 1966 to
2009. Citations were identified through a systematic search of Medline, Embase and …

Relative frequency and morphology of cancers in STK11 mutation carriers

W Lim, S Olschwang, JJ Keller, AM Westerman… - Gastroenterology, 2004 - Elsevier
Background & Aims: There is limited data on the spectrum and risk for cancer associated
with germline serine/threonine protein kinase 11 (STK11) mutations that cause Peutz …

Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10 year prospective study

CJ Groves, BP Saunders, AD Spigelman, RKS Phillips - Gut, 2002 - gut.bmj.com
Background: Duodenal cancer is one of the leading causes of death in familial
adenomatous polyposis (FAP) patients. An endoscopic surveillance programme was …

Cancer and the Peutz-Jeghers syndrome.

AD Spigelman, V Murday, RK Phillips - Gut, 1989 - gut.bmj.com
Among 72 patients with the Peutz-Jeghers syndrome malignant tumours have developed in
16 (22%) of whom all but one have died. There were nine gastrointestinal and seven …

[PDF][PDF] Hereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutation-negative kindreds

RJ Scott, M McPhillips, CJ Meldrum… - The American Journal of …, 2001 - cell.com
Hereditary nonpolyposis colorectal cancer (HNPCC) describes the condition of a disparate
group of families that have in common a predisposition to colorectal cancer in the absence …

The variable effect on proliferation of a colon cancer cell line by the citrus fruit flavonoid Naringenin

HR Frydoonfar, DR McGrath… - Colorectal Disease, 2003 - Wiley Online Library
Objective Naringenin, a naturally occurring flavonoid found in citrus fruits, is known to have
anticarcinogenic properties. We have examined the effect of Naringenin on cell proliferation …