Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
OJ Sansom, KR Reed, AJ Hayes, H Ireland… - Genes & …, 2004 - genesdev.cshlp.org
Although Apc is well characterized as a tumor-suppressor gene in the intestine, the precise
mechanism of this suppression remains to be defined. Using a novel inducible Ahcre …
mechanism of this suppression remains to be defined. Using a novel inducible Ahcre …
[HTML][HTML] Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and …
Background The benefits and safety of medications for attention-deficit hyperactivity disorder
(ADHD) remain controversial, and guidelines are inconsistent on which medications are …
(ADHD) remain controversial, and guidelines are inconsistent on which medications are …
Mental health of prisoners: prevalence, adverse outcomes, and interventions
More than 10 million people are imprisoned worldwide, and the prevalence of all
investigated mental disorders is higher in prisoners than in the general population. Although …
investigated mental disorders is higher in prisoners than in the general population. Although …
The Pittsburgh sleep diary
TH Monk, CF REYNOLDS III, DJ Kupfer… - Journal of sleep …, 1994 - Wiley Online Library
Increasingly, there is a need in both research and clinical practice to document and quantify
sleep and waking behaviors in a comprehensive manner. The Pittsburgh Sleep Diary …
sleep and waking behaviors in a comprehensive manner. The Pittsburgh Sleep Diary …
[HTML][HTML] Long-term and recent trends in hypertension awareness, treatment, and control in 12 high-income countries: an analysis of 123 nationally representative …
Background Antihypertensive medicines are effective in reducing adverse cardiovascular
events. Our aim was to compare hypertension awareness, treatment, and control, and how …
events. Our aim was to compare hypertension awareness, treatment, and control, and how …
Variability in patterns of recurrence after resection of primary retroperitoneal sarcoma (RPS): a report on 1007 patients from the multi-institutional collaborative RPS …
Background: Retroperitoneal sarcomas (RPS) are rare tumors composed of several well
defined histologic subtypes. The aim of this study was to analyze patterns of recurrence and …
defined histologic subtypes. The aim of this study was to analyze patterns of recurrence and …
[HTML][HTML] UKPDS outcomes model 2: a new version of a model to simulate lifetime health outcomes of patients with type 2 diabetes mellitus using data from the 30 year …
Aims/hypothesis The aim of this project was to build a new version of the United Kingdom
Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS-OM1), a patient-level …
Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS-OM1), a patient-level …
The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells
PJP Coopman, MTH Do, M Barth, ET Bowden… - Nature, 2000 - nature.com
Syk is a protein tyrosine kinase that is widely expressed in haematopoietic cells. It is
involved in coupling activated immunoreceptors to downstream signalling events that …
involved in coupling activated immunoreceptors to downstream signalling events that …
Substance use disorders in prisoners: an updated systematic review and meta‐regression analysis in recently incarcerated men and women
Aims The aims were to (1) estimate the prevalence of alcohol and drug use disorders in
prisoners on reception to prison and (2) estimate and test sources of between study …
prisoners on reception to prison and (2) estimate and test sources of between study …
Development and external validation of two nomograms to predict overall survival and occurrence of distant metastases in adults after surgical resection of localised …
D Callegaro, R Miceli, S Bonvalot, P Ferguson… - The Lancet …, 2016 - thelancet.com
Summary Background The current American Joint Committee on Cancer/Union for
International Cancer Control (AJCC/UICC) staging system does not have sufficient details to …
International Cancer Control (AJCC/UICC) staging system does not have sufficient details to …