Pseudogenes are commonly encountered during investigation of the genomes of a wide
range of life forms. This review concentrates on vertebrate, and in particular mammalian …

Amelogenesis imperfecta (AI) is the name given to a heterogeneous group of conditions
characterized by inherited developmental enamel defects. AI enamel is abnormally thin, soft …

Oral Diseases (2011) 17 (Suppl. 1), 42–57 Oral submucous fibrosis (OSF) is a chronic,
insidious disease caused by areca nut use, and is associated with both significant morbidity …

Background Real-time PCR is increasingly being adopted for RNA quantification and
genetic analysis. At present the most popular real-time PCR assay is based on the …

Primary microcephaly (MIM 251200) is an autosomal recessive neurodevelopmental
condition in which there is a global reduction in cerebral cortex volume, to a size …

The combination of recessively inherited cone-rod dystrophy (CRD) and amelogenesis
imperfecta (AI) was first reported by Jalili and Smith in 1988 in a family subsequently linked …

Healthy dental enamel is the hardest and most highly mineralized human tissue. Though
acellular, nonvital, and without capacity for turnover or repair, it can nevertheless last a …

Amelogenesis imperfecta (AI) describes a heterogeneous group of inherited dental enamel
defects reflecting failure of normal amelogenesis. Ameloblastin (AMBN) is the second most …

Alu sequences are frequently encountered during study of human genomic nucleic acid and
form a major component of repetitive DNA. This review describes the origin of Alu …

Heimler syndrome (HS) is a rare recessive disorder characterized by sensorineural hearing
loss (SNHL), amelogenesis imperfecta, nail abnormalities, and occasional or late-onset …