The histopathology of the pancreas in type I (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom
AK Foulis, CN Liddle, MA Farquharson, JA Richmond… - Diabetologia, 1986 - Springer
A 25-year computerised survey of deaths in the United Kingdom among diabetic patients of
19 years of age and under was performed. Suitable pancreatic material was available in 119 …
19 years of age and under was performed. Suitable pancreatic material was available in 119 …
A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study
MJ Proctor, DS Morrison, D Talwar, SM Balmer… - European journal of …, 2011 - Elsevier
INTRODUCTION: Components of the systemic inflammatory response, combined to form
inflammation-based prognostic scores (modified Glasgow Prognostic Score (mGPS) …
inflammation-based prognostic scores (modified Glasgow Prognostic Score (mGPS) …
Analysis of islet inflammation in human type 1 diabetes
A Willcox, SJ Richardson, AJ Bone… - Clinical & …, 2009 - academic.oup.com
The immunopathology of type 1 diabetes (T1D) has proved difficult to study in man because
of the limited availability of appropriate samples, but we now report a detailed study charting …
of the limited availability of appropriate samples, but we now report a detailed study charting …
Immunopathology of the human pancreas in type-I diabetes
SJ Richardson, A Willcox, AJ Bone, NG Morgan… - Seminars in …, 2011 - Springer
Type 1 diabetes is a chronic autoimmune disease characterised by the selective destruction
of pancreatic beta (β) cells. The understanding of the aetiology of this disease has increased …
of pancreatic beta (β) cells. The understanding of the aetiology of this disease has increased …
[HTML][HTML] The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes
SJ Richardson, A Willcox, AJ Bone, AK Foulis… - Diabetologia, 2009 - Springer
Aims/hypothesis Evidence that the beta cells of human patients with type 1 diabetes can be
infected with enterovirus is accumulating, but it remains unclear whether such infections …
infected with enterovirus is accumulating, but it remains unclear whether such infections …
Pancreatic pathology in type 1 diabetes mellitus
SJ Richardson, NG Morgan, AK Foulis - Endocrine pathology, 2014 - Springer
Type 1 diabetes is a multifactorial disease resulting from a complex interplay between host
genetics, the immune system and the environment, that culminates in the destruction of …
genetics, the immune system and the environment, that culminates in the destruction of …
Immunoreactive α-interferon in insulin-secreting β cells in type 1 diabetes mellitus
AK Foulis, MA Farquharson, A Meager - The Lancet, 1987 - Elsevier
Of 37 pancreases removed at necropsy from patients with type 1 diabetes 34 had residual β
cells. In 33 of the 34 the β cells were positive for immunoreactive α-interferon, and this …
cells. In 33 of the 34 the β cells were positive for immunoreactive α-interferon, and this …
[HTML][HTML] An inflammation-based prognostic score (mGPS) predicts cancer survival independent of tumour site: a Glasgow Inflammation Outcome Study
MJ Proctor, DS Morrison, D Talwar, SM Balmer… - British journal of …, 2011 - nature.com
Methods: Patients (n= 21 669) who had an incidental blood sample taken between 2000
and 2006 for C-reactive protein, albumin and calcium (and liver function tests where …
and 2006 for C-reactive protein, albumin and calcium (and liver function tests where …
Differential insulitic profiles determine the extent of β-cell destruction and the age at onset of type 1 diabetes
Type 1 diabetes (T1D) results from a T cell–mediated destruction of pancreatic β-cells
following the infiltration of leukocytes (including CD8+, CD4+, and CD20+ cells) into and …
following the infiltration of leukocytes (including CD8+, CD4+, and CD20+ cells) into and …
Positive mobilization margins alone do not influence survival following pancreatico-duodenectomy for pancreatic ductal adenocarcinoma
Objective: To determine the prognostic influence of residual tumor at or within 1 mm of the
mobilization margins (R1 Mobilization) compared with transection margins (R1 Transection) …
mobilization margins (R1 Mobilization) compared with transection margins (R1 Transection) …