The Lancet Commission on diabetes: using data to transform diabetes care and patient lives
Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …
awakened to the fragility of human health and the interdependence of the ecosystem …
[HTML][HTML] Impact of age at type 2 diabetes mellitus diagnosis on mortality and vascular complications: systematic review and meta-analyses
Aims/hypothesis Few studies examine the association between age at diagnosis and
subsequent complications from type 2 diabetes. This paper aims to summarise the risk of …
subsequent complications from type 2 diabetes. This paper aims to summarise the risk of …
[PDF][PDF] Epidemiology of hyperuricemia and gout
AJ Luk, PA Simkin - Am J Manag Care, 2005 - ajmc.s3.amazonaws.com
Gout is an increasingly common medical problem. The traditional risk factors of male sex
and high red meat or alcohol consumption have been joined by a wave of newer risk factors …
and high red meat or alcohol consumption have been joined by a wave of newer risk factors …
Observation of electron-antineutrino disappearance at Daya Bay
…, JL Liu, S Liu, X Liu, YB Liu, C Lu, HQ Lu, A Luk… - Physical Review Letters, 2012 - APS
Abstract The Daya Bay Reactor Neutrino Experiment has measured a nonzero value for the
neutrino mixing angle θ 13 with a significance of 5.2 standard deviations. Antineutrinos from …
neutrino mixing angle θ 13 with a significance of 5.2 standard deviations. Antineutrinos from …
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
…, JM Sommer, M Tigges, D Sabatino, A Luk… - Nature medicine, 2006 - nature.com
We have previously shown that a single portal vein infusion of a recombinant adeno-
associated viral vector (rAAV) expressing canine Factor IX (F. IX) resulted in long-term …
associated viral vector (rAAV) expressing canine Factor IX (F. IX) resulted in long-term …
Identification of a nuclear receptor for bile acids
…, AY Okamoto, JJ Repa, H Tu, RM Learned, A Luk… - Science, 1999 - science.org
Bile acids are essential for the solubilization and transport of dietary lipids and are the major
products of cholesterol catabolism. Results presented here show that bile acids are …
products of cholesterol catabolism. Results presented here show that bile acids are …
Role of LXRs in control of lipogenesis
JR Schultz, H Tu, A Luk, JJ Repa… - Genes & …, 2000 - genesdev.cshlp.org
The discovery of oxysterols as the endogenous liver X receptor (LXR) ligands and
subsequent gene targeting studies in mice provided strong evidence that LXR plays a …
subsequent gene targeting studies in mice provided strong evidence that LXR plays a …
Improved measurement of electron antineutrino disappearance at Daya Bay
…, JC Liu, JL Liu, YB Liu, C Lu, HQ Lu, A Luk… - Chinese …, 2013 - iopscience.iop.org
We report an improved measurement of the neutrino mixing angle θ 13 from the Daya Bay
Reactor Neutrino Experiment. We exclude a zero value for sin 2 2θ 13 with a significance of …
Reactor Neutrino Experiment. We exclude a zero value for sin 2 2θ 13 with a significance of …
[HTML][HTML] Hemophilia B gene therapy with a high-specific-activity factor IX variant
LA George, SK Sullivan, A Giermasz… - … England Journal of …, 2017 - Mass Medical Soc
Background The prevention of bleeding with adequately sustained levels of clotting factor,
after a single therapeutic intervention and without the need for further medical intervention …
after a single therapeutic intervention and without the need for further medical intervention …
Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A
…, N Dodd, K Nugent, G Vigliani, A Luk… - Blood, The Journal …, 2014 - ashpublications.org
This phase 3 pivotal study evaluated the safety, efficacy, and pharmacokinetics of a
recombinant FVIII Fc fusion protein (rFVIIIFc) for prophylaxis, treatment of acute bleeding …
recombinant FVIII Fc fusion protein (rFVIIIFc) for prophylaxis, treatment of acute bleeding …