Primary ciliary dyskinesia is a genetically and clinically heterogeneous syndrome. Impaired
function of motile cilia causes failure of mucociliary clearance. Patients typically present with …

The core axoneme structure of both the motile cilium and sperm tail has the same
ultrastructural 9+ 2 microtubular arrangement. Thus, it can be expected that genetic defects …

Background The examination of ciliary ultrastructure in a nasal sample remains a definitive
diagnostic test for primary ciliary dyskinesia (PCD). Methods The quantitative assessment of …

The diagnosis of primary ciliary dyskinesia is often confirmed with standard, albeit complex
and expensive, tests. In many cases, however, the diagnosis remains difficult despite the …

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous inherited disorder arising
from dysmotility of motile cilia and sperm. This is associated with a variety of ultrastructural …

BACKGROUND: Bronchiectasis has a number of causes. Their prevalence is not well
documented. The aim of this study was to identify aetiology in a population of patients …

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous recessive disorder
characterized by defective cilia and flagella motility. Chronic destructive-airway disease is …

Deficient type I interferon-β and type III interferon-λ induction by rhinoviruses has previously
been reported in mild/moderate atopic asthmatic adults. No studies have yet investigated if …

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder caused by cilia
and sperm dysmotility. About 12% of cases show perturbed 9+ 2 microtubule cilia structure …

Defects in motile cilia and sperm flagella cause primary ciliary dyskinesia (PCD),
characterized by chronic airway disease, infertility, and left-right laterality disturbances …