The coagulopathy of chronic liver disease

A Tripodi, PM Mannucci - New England Journal of Medicine, 2011 - Mass Medical Soc
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[PDF][PDF] Coagulation disorders and hemostasis in liver disease: pathophysiology and critical assessment of current management

…, BG Macik, PG Northup, KR Reddy, A Tripodi… - …, 2006 - Wiley Online Library
Normal coagulation has classically been conceptualized as a Y‐shaped pathway, with
distinct “intrinsic” and “extrinsic” components initiated by factor XII or factor VIIa/tissue factor …

Hemostasis and thrombosis in patients with liver disease: the ups and downs

…, PG Northup, M Senzolo, RT Stravitz, A Tripodi… - Journal of …, 2010 - Elsevier
Patients with chronic or acute liver failure frequently show profound abnormalities in their
hemostatic system. Whereas routine laboratory tests of hemostasis suggest these …

Hypercoagulability of COVID‐19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis

…, A Pesenti, F Peyvandi, A Tripodi - … of thrombosis and …, 2020 - Wiley Online Library
Background The severe inflammatory state secondary to COVID‐19 leads to a severe
derangement of hemostasis that has been recently described as a state of disseminated …

[HTML][HTML] Update of the guidelines for lupus anticoagulant detection

V Pengo, A Tripodi, G Reber, JH Rand, TL Ortel… - Journal of Thrombosis …, 2009 - Elsevier
One of the conclusions of the subcommittee meeting on Lupus Anticoagulant/Phospholipid
dependent antibodies, held in Geneva on 2007, was the need to update the guidelines on …

[HTML][HTML] d-Dimer Testing to Determine the Duration of Anticoagulation Therapy

…, S Testa, AWA Lensing, A Tripodi - … England Journal of …, 2006 - Mass Medical Soc
Background The optimal duration of oral anticoagulation in patients with idiopathic venous
thromboembolism is uncertain. Testing of d-dimer levels may play a role in the assessment …

[HTML][HTML] COVID-19 and haemostasis: a position paper from Italian Society on Thrombosis and Haemostasis (SISET)

…, P Gresele, M Marchetti, R Marcucci, A Tripodi - Blood …, 2020 - ncbi.nlm.nih.gov
The ongoing pandemic of Coronavirus disease 2019 (COVID-19) is severely challenging
healthcare systems all around the world, with the need to provide intensive care to a …

An imbalance of pro-vs anti-coagulation factors in plasma from patients with cirrhosis

A Tripodi, M Primignani, V Chantarangkul, A Dell'Era… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Patients with cirrhosis have an increased tendency to develop
thromboses despite the longer coagulation times of their plasma, compared with that of …

[PDF][PDF] Evidence of normal thrombin generation in cirrhosis despite abnormal conventional coagulation tests

A Tripodi, F Salerno, V Chantarangkul, M Clerici… - …, 2005 - Wiley Online Library
The role played by coagulation defects in the occurrence of bleeding in cirrhosis is still
unclear. This is partly due to the lack of tests that truly reflect the balance of procoagulant …

[PDF][PDF] Thrombin generation in patients with cirrhosis: the role of platelets

A Tripodi, M Primignani, V Chantarangkul… - …, 2006 - Wiley Online Library
Coagulation factor defects, thrombocytopenia, and thrombocytopathy are associated with
cirrhosis. However, bleeding in patients who have cirrhosis does not entirely correlate with …