User profiles for "author:Aarnoud Huissoon"

Aarnoud P Huissoon

Immunology, Birmingham Heartlands Hospital, UK
Verified email at uhb.nhs.uk
Cited by 6830

Subcutaneous and sublingual immunotherapy for seasonal allergic rhinitis: a systematic review and indirect comparison

J Dretzke, A Meadows, N Novielli, A Huissoon… - Journal of allergy and …, 2013 - Elsevier
BACKGROUND: Severe allergic rhinitis uncontrolled by pharmacotherapy can adversely
affect quality of life. Both subcutaneous immunotherapy (SCIT) and sublingual …

A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis

A Meadows, B Kaambwa, N Novielli, A Huissoon… - 2013 - bura.brunel.ac.uk
Severe allergic rhinitis uncontrolled by conventional medication can substantially affect
quality of life. Immunotherapy involves administering increasing doses of a specific allergen …

[HTML][HTML] British Lung Foundation/United Kingdom Primary Immunodeficiency Network consensus statement on the definition, diagnosis, and management of …

JR Hurst, N Verma, D Lowe, HE Baxendale… - The Journal of Allergy …, 2017 - Elsevier
A proportion of people living with common variable immunodeficiency disorders develop
granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a …

Use and interpretation of diagnostic vaccination in primary immunodeficiency: a working group report of the Basic and Clinical Immunology Interest Section of the …

JS Orange, M Ballow, ER Stiehm, ZK Ballas… - Journal of Allergy and …, 2012 - Elsevier
A major diagnostic intervention in the consideration of many patients suspected to have
primary immunodeficiency diseases (PIDDs) is the application and interpretation of …

[PDF][PDF] Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease

KJ Carss, G Arno, M Erwood, J Stephens… - The American Journal of …, 2017 - cell.com
Inherited retinal disease is a common cause of visual impairment and represents a highly
heterogeneous group of conditions. Here, we present findings from a cohort of 722 …

COVID-19 in patients with primary and secondary immunodeficiency: the United Kingdom experience

AM Shields, SO Burns, S Savic, AG Richter… - Journal of Allergy and …, 2021 - Elsevier
Background As of November 2020, severe acute respiratory syndrome coronavirus 2 has
resulted in 55 million infections worldwide and more than 1.3 million deaths from …

Inhibition of T cell apoptosis in the rheumatoid synovium.

M Salmon, D Scheel-Toellner… - The Journal of …, 1997 - Am Soc Clin Investig
Synovial T cells in rheumatoid arthritis are highly differentiated and express a phenotype
suggesting susceptibility to apoptosis (CD45RB dull, CD45RO bright, Bcl-2 low, Bax high …

[HTML][HTML] Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans

P Tuijnenburg, HL Allen, SO Burns, D Greene… - Journal of allergy and …, 2018 - Elsevier
Background The genetic cause of primary immunodeficiency disease (PID) carries
prognostic information. Objective We conducted a whole-genome sequencing study …

Hypochlorous acid regulates neutrophil extracellular trap release in humans

LJ Palmer, PR Cooper, MR Ling… - Clinical & …, 2012 - academic.oup.com
Neutrophil extracellular traps (NETs) comprise extracellular chromatin and granule protein
complexes that immobilize and kill bacteria. NET release represents a recently discovered …

Whole-genome sequencing of a sporadic primary immunodeficiency cohort

JED Thaventhiran, H Lango Allen, OS Burren, W Rae… - Nature, 2020 - nature.com
Primary immunodeficiency (PID) is characterized by recurrent and often life-threatening
infections, autoimmunity and cancer, and it poses major diagnostic and therapeutic …