Severe liver disease in pregnancy is rare. Pregnancy-related liver disease is the most
frequent cause of liver dysfunction in pregnancy and provides a real threat to fetal and …

Acute-on-chronic liver failure combines an acute deterioration in liver function in an
individual with pre-existing chronic liver disease and hepatic and extrahepatic organ …

Characteristics for an optimal liver biopsy specimen were recently defined as 20 to 25 mm
long and/or containing more than 11 complete portal tracts (CPTs). A systematic review of …

Stem cells are undifferentiated long-lived cells that are capable of many rounds of division.
Here we show that adult human liver cells can be derived from stem cells originating in the …

The number of donor organs suitable for liver transplantation is restricted by cold
preservation and ischemia–reperfusion injury. We present the first patients transplanted …

Background & Aims Chronic infection with hepatitis B virus (HBV) progresses through
different phases. The first, called the immune-tolerant phase, has been associated with a …

Background & Aims Hepatocellular adenomas (HCAs) are benign liver tumors that can be
assigned to molecular subtypes based on inactivating mutations in hepatocyte nuclear factor …

Summary of Key Recommendations Diagnosis It is recommended that the diagnosis of veno‐
occlusive disease (sinusoidal obstruction syndrome)[VOD (SOS)] be based primarily on …

Cholangiocarcinoma of the intrahepatic and extrahepatic bile ducts develops through a
multistep histopathologic sequence. Premalignant or non-invasive neoplastic lesions of bile …

Primary liver carcinomas with both hepatocytic and cholangiocytic differentiation have been
referred to as “combined (or mixed) hepatocellular‐cholangiocarcinoma.” These tumors …