Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ …

LS Hellgren, A Olsson, A Kaufeldt… - Journal of clinical …, 2022 - jcp.bmj.com
Aims Upregulation of the telomerase reverse transcriptase (TERT) gene is a frequent finding
in follicular thyroid carcinomas (FTCs) with metastatic features. The augmented expression …

A method to assess the distribution and frequency of plasma cells and plasma cell precursors in autoimmune hepatitis

CA Rubio, K Truskaite, R Rajani, A Kaufeldt… - Anticancer …, 2013 - ar.iiarjournals.org
Chronic inflammation exhibiting interface hepatitis and plasma cells in hematoxylin-eosin
(H&E)-stained sections is typical of autoimmune hepatitis (AIH), a non-resolving …

β-catenin helices in the cytoplasm of sessile serrated adenoma/polyps and conventional colorectal adenomas

CA Rubio, A Kaufeldt, R Koha, M Ushoida… - Anticancer …, 2015 - ar.iiarjournals.org
Initiation and progression in conventional adenomas is triggered by deregulation of WNT/β-
catenin signaling. In the absence of WNT signal (off-state), β-catenin prevents …

Proteomic profiling of diffuse Large b-cell lymphomas

A Kwiecińska, A Porwit, N Souchelnytskyi, A Kaufeldt… - Pathobiology, 2018 - karger.com
Objective: The aim of this study was to identify differences in proteome profiles of diffuse
large B-cell lymphoma (DLBCL) of nongerminal center (non-GC) versus GC type in the …

Maspin, a marker of serrated colorectal polyps

CA Rubio, A Kaufeldt, J Björk, E Jaramillo - Anticancer Research, 2015 - ar.iiarjournals.org
The serine proteinase inhibitor maspin is a tumor-suppressor protein that stimulates
apoptosis and inhibits motility, invasion and cancer metastasis. Mutant maspin galvanises …

β-catenin Helices in the cytoplasm of sporadic and FAP duodenal adenomas

CA Rubio, A Kaufeldt, R Kohan, M Ushoida… - Anticancer …, 2015 - ar.iiarjournals.org
Background: Initiation and progression in conventional adenomas is triggered by
deregulation of Wnt/β-catenin signaling. In the absence of Wnt signal (off-state), β-catenin …

Maspin highlights colorectal serrated polyps: preliminary findings

CA Rubio, A Kaufeldt - in vivo, 2015 - iv.iiarjournals.org
Aims: Maspin, a 42-kDa serine proteinase inhibitor, is a tumor suppressor protein that
stimulates apoptosis and inhibits motility, invasion and cancer metastasis. Mutant maspin …

Paucity of synaptophysin‐expressing cells in B arrett's mucosa

CA Rubio, A Kaufeldt - Histopathology, 2013 - Wiley Online Library
Aims To assess synaptophysin expression in columnar‐lined oesophageal mucosa showing
either goblet cells, known as intestinal metaplasia, or with accompanying oxyntic glands or …

Expression and Prognostic Role of PD-L1 in Lung Cancer

C Ortiz-Villalon, L Kis, M Andersson… - Archives of Pathology …, 2016 - go.gale.com
Context: The PD1/PD-L1 checkpoint inhibitor pathway has recently received great interest in
lung cancer owing to the development of specific PD1 or PD-L1 inhibitors that have shown …