[HTML][HTML] Genetics and cardiac channelopathies
O Campuzano, P Beltrán-Álvarez, A Iglesias… - Genetics in …, 2010 - Elsevier
Sudden cardiac death is a major contributor to mortality in industrialized nations; in fact, it is
the cause of more deaths than acquired immune deficiency syndrome, lung and breast …
the cause of more deaths than acquired immune deficiency syndrome, lung and breast …
[HTML][HTML] Identification of a genetic locus for familial atrial fibrillation
R Brugada, T Tapscott… - … England Journal of …, 1997 - Mass Medical Soc
Background Atrial fibrillation, the most common sustained cardiac-rhythm disturbance,
affects over 2 million Americans and accounts for one third of all strokes in patients over 65 …
affects over 2 million Americans and accounts for one third of all strokes in patients over 65 …
Negative autopsy and sudden cardiac death
O Campuzano, C Allegue, S Partemi, A Iglesias… - International journal of …, 2014 - Springer
Forensic medicine defines the unexplained sudden death as a death with a non-conclusive
diagnosis after autopsy. Molecular diagnosis is being progressively incorporated in …
diagnosis after autopsy. Molecular diagnosis is being progressively incorporated in …
Genetic basis of dilated cardiomyopathy
A Pérez-Serra, R Toro, G Sarquella-Brugada… - International journal of …, 2016 - Elsevier
Dilated cardiomyopathy is a rare cardiac disease characterized by left ventricular dilatation
and systolic dysfunction leading to heart failure and sudden cardiac death. Currently …
and systolic dysfunction leading to heart failure and sudden cardiac death. Currently …
A Missense Mutation in the Sodium Channel β2 Subunit Reveals SCN2B as a New Candidate Gene for Brugada Syndrome
H Riuró, P Beltran‐Alvarez, A Tarradas… - Human …, 2013 - Wiley Online Library
ABSTRACT B rugada S yndrome (B r S) is a familial disease associated with sudden cardiac
death. A 20%–25% of B r S patients carry genetic defects that cause loss‐of‐function of the …
death. A 20%–25% of B r S patients carry genetic defects that cause loss‐of‐function of the …
Coexistence of epilepsy and Brugada syndrome in a family with SCN5A mutation
Cardiac arrhythmias are associated with abnormal channel function due to mutations in ion
channel genes. Epilepsy is a disorder of neuronal function also involving abnormal channel …
channel genes. Epilepsy is a disorder of neuronal function also involving abnormal channel …
Increase in sudden death from coronary artery disease in young adults
D Arzamendi, B Benito, H Tizon-Marcos, J Flores… - American heart …, 2011 - Elsevier
BACKGROUND: Sudden cardiac death (SCD) is the most common cause of death in adults
aged< 65 years, making it a major public health problem. A growing incidence in coronary …
aged< 65 years, making it a major public health problem. A growing incidence in coronary …
[HTML][HTML] Natural and undetermined sudden death: value of post-mortem genetic investigation
O Sanchez, O Campuzano, A Fernández-Falgueras… - PLoS …, 2016 - journals.plos.org
Background Sudden unexplained death may be the first manifestation of an unknown
inherited cardiac disease. Current genetic technologies may enable the unraveling of an …
inherited cardiac disease. Current genetic technologies may enable the unraveling of an …
Arrhythmogenic right ventricular cardiomyopathy: severe structural alterations are associated with inflammation
O Campuzano, M Alcalde, A Iglesias… - Journal of clinical …, 2012 - jcp.bmj.com
Aim Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a rare cardiomyopathy
associated with sudden cardiac death. It is characterised by a progressive right ventricle …
associated with sudden cardiac death. It is characterised by a progressive right ventricle …
Electroanatomic and pathologic right ventricular outflow tract abnormalities in patients with Brugada syndrome
Background: The prevalence and significance of structural abnormalities in Brugada
syndrome (BrS) are still largely debated. Objectives: The authors investigated the …
syndrome (BrS) are still largely debated. Objectives: The authors investigated the …