Objectives: To develop evidence-based guideline recommendations through a systematic
review of the literature to establish standard molecular biomarker testing of colorectal cancer …

The neurotrophic tyrosine receptor kinase (NTRK) gene family encodes three tropomyosin
receptor kinases (TRKA, TRKB, TRKC) that contribute to central and peripheral nervous …

Over recent decades we have witnessed a shift in the anatomical distribution of gastric
cancer (GC), which increasingly originates from the proximal stomach near the junction with …

BACKGROUND & AIMS: Crohn's disease commonly recurs after intestinal resection. We
evaluated whether the administration of infliximab after resective intestinal surgery for …

The HER-2/neu protein is intimately involved with normal cell proliferation and tissue growth
and is extensively homologous and related to the epidermal growth factor receptor. HER …

Autophagy is a lysosome-dependent degradative process that protects cancer cells from
multiple stresses. In preclinical models, autophagy inhibition with chloroquine (CQ) …

ABSTRACT The CagA protein of Helicobacter pylori is an immunogenic antigen of variable
size and unknown function that has been associated with increased virulence as well as two …

The regulation and stem cell origin of normal and neoplastic gastric glands are uncertain.
Here, we show that Mist1 expression marks quiescent stem cells in the gastric corpus …

Heme oxygenase (HO)-1 and its metabolic product carbon monoxide (CO) play regulatory
roles in acute inflammatory states. In this study, we demonstrate that CO administration is …

LIN28B is a homologue of LIN28 that induces pluripotency when expressed in conjunction
with OCT4, SOX2, and KLF4 in somatic fibroblasts. LIN28B represses biogenesis of let-7 …