User profiles for "author:Ayse Ayhan"
Ayse AyhanProfessor of Pathology Verified email at hacettepe.edu.tr Cited by 8746 |
[HTML][HTML] High grade serous ovarian carcinomas originate in the fallopian tube
SI Labidi-Galy, E Papp, D Hallberg, N Niknafs… - Nature …, 2017 - nature.com
High-grade serous ovarian carcinoma (HGSOC) is the most frequent type of ovarian cancer
and has a poor outcome. It has been proposed that fallopian tube cancers may be …
and has a poor outcome. It has been proposed that fallopian tube cancers may be …
Pathology and pathogenesis of adenomyosis
Adenomyosis represents a unique pathophysiological condition in which normal-appearing
endometrial mucosa resides within myometrium and is thus protected from menstrual …
endometrial mucosa resides within myometrium and is thus protected from menstrual …
[HTML][HTML] Cancer-associated mutations in endometriosis without cancer
MS Anglesio, N Papadopoulos, A Ayhan… - … England Journal of …, 2017 - Mass Medical Soc
Background Endometriosis, defined as the presence of ectopic endometrial stroma and
epithelium, affects approximately 10% of reproductive-age women and can cause pelvic …
epithelium, affects approximately 10% of reproductive-age women and can cause pelvic …
Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma
Ovarian clear cell carcinoma (CCC) is one of the most malignant types of ovarian
carcinomas, particularly at advanced stages. Unlike the more common type of ovarian …
carcinomas, particularly at advanced stages. Unlike the more common type of ovarian …
The inflammatory cytokine tumor necrosis factor-α generates an autocrine tumor-promoting network in epithelial ovarian cancer cells
H Kulbe, R Thompson, JL Wilson, S Robinson… - Cancer research, 2007 - AACR
Constitutive expression of the inflammatory cytokine tumor necrosis factor-α (TNF-α) is
characteristic of malignant ovarian surface epithelium. We investigated the hypothesis that …
characteristic of malignant ovarian surface epithelium. We investigated the hypothesis that …
Mature cystic teratomas of the ovary: case series from one institution over 34 years
A Ayhan, O Bukulmez, C Genc, BS Karamursel… - European Journal of …, 2000 - Elsevier
Objective: To evaluate bilaterality, complications and malignant changes of mature cystic
teratomas of the ovary. Study design: Retrospective study of 501 patients operated at …
teratomas of the ovary. Study design: Retrospective study of 501 patients operated at …
Loss of ARID1A expression is an early molecular event in tumor progression from ovarian endometriotic cyst to clear cell and endometrioid carcinoma
Objectives ARID1A is a recently identified tumor suppressor participating in chromatin
remodeling. Somatic inactivating mutations of ARID1A and loss of its expression occur …
remodeling. Somatic inactivating mutations of ARID1A and loss of its expression occur …
Cystic and adenofibromatous clear cell carcinomas of the ovary: distinctive tumors that differ in their pathogenesis and behavior: a clinicopathologic analysis of 122 …
Ovarian clear cell carcinomas (CCC) typically present as large adnexal, stage I tumors and
are generally considered highly malignant. They are frequently associated with …
are generally considered highly malignant. They are frequently associated with …
[PDF][PDF] Inhibition of spleen tyrosine kinase potentiates paclitaxel-induced cytotoxicity in ovarian cancer cells by stabilizing microtubules
Resistance to chemotherapy represents a major obstacle for long-term remission, and
effective strategies to overcome drug resistance would have significant clinical impact. We …
effective strategies to overcome drug resistance would have significant clinical impact. We …
Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas
We examined the expression of p34cdc2 and its kinase activity in human gastric and colonic
carcinoma cell lines and carcinoma tissues and studied its relation with a tumor‐suppressor …
carcinoma cell lines and carcinoma tissues and studied its relation with a tumor‐suppressor …