KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation

…, EYC Hsia, C Izumiya… - Proceedings of the …, 2010 - National Acad Sciences
Localized chromatin modifications of histone tails play an important role in regulating gene
transcription, and aberration of these processes leads to carcinogenesis. Methylated histone …

[HTML][HTML] Increased killer inhibitory receptor KIR2DL1 expression among natural killer cells in women with pelvic endometriosis

N Maeda, C Izumiya, Y Yamamoto, H Oguri… - Fertility and sterility, 2002 - Elsevier
Objective: To investigate the host immunologic response to endometriosis in terms of killer
inhibitory receptor (KIR) expression by natural killer (NK) cells. Design: Case-control study of …

[PDF][PDF] KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4

…, RR Davis, CG Tepper, K Nakano, C Izumiya… - Cell reports, 2022 - cell.com
Kaposi sarcoma-associated herpesvirus (KSHV) establishes a latent infection in the cell
nucleus, but where KSHV episomal genomes are tethered and the mechanisms underlying …

Kaposi's sarcoma-associated herpesvirus K-bZIP is a coregulator of K-Rta: physical association and promoter-dependent transcriptional repression

…, SF Lin, T Ellison, LY Chen, C Izumiya… - Journal of …, 2003 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is a human gammaherpesvirus that has
been implicated in the pathogenesis of Kaposi's sarcoma and B-cell neoplasms. The …

[HTML][HTML] Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells

GL Mayeur, WJ Kung, A Martinez, C Izumiya… - Journal of Biological …, 2005 - ASBMB
The androgen receptor (AR) dynamically assembles and disassembles multicomponent
receptor complexes in order to respond rapidly and reversibly to fluctuations in androgen …

A lytic viral long noncoding RNA modulates the function of a latent protein

…, S Huerta, B Shevchenko, DH Wang, C Izumiya… - Journal of …, 2014 - Am Soc Microbiol
Latent Kaposi's sarcoma-associated herpesvirus (KSHV) episomes are coated with viral
latency-associated nuclear antigen (LANA). In contrast, LANA rapidly disassociates from …

[PDF][PDF] Role of NK cells and HLA-G in endometriosis

N Maeda, C Izumiya, K Taniguchi… - … Biosci (Schol Ed), 2012 - article.imrpress.com
Impaired natural killer (NK) activity in women with endometriosis is thought to promote
implantation and progression of endometrial tissue, in accord with Sampson's hypothesis …

Kaposi's sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP

Y Izumiya, C Izumiya, A Van Geelen, DH Wang… - Journal of …, 2007 - Am Soc Microbiol
The oncogenic herpesvirus, Kaposi's sarcoma-associated herpesvirus, also identified as
human herpesvirus 8, contains genes producing proteins that control transcription and …

[HTML][HTML] Kaposi's sarcoma-associated herpesvirus K-Rta exhibits SUMO-targeting ubiquitin ligase (STUbL) like activity and is essential for viral reactivation

…, KY Kim, M Pochampalli, C Izumiya… - PLoS …, 2013 - journals.plos.org
The small ubiquitin-like modifier (SUMO) is a protein that regulates a wide variety of cellular
processes by covalent attachment of SUMO moieties to a diverse array of target proteins …

Expression of inhibitory‐motif killer immunoglobulin‐like receptor, KIR2DL1, is increased in natural killer cells from women with pelvic endometriosis

S Matsuoka, N Maeda, C Izumiya… - American Journal of …, 2005 - Wiley Online Library
Problem: We investigated inhibitory and activation motif expression of killer immunoglobulin‐
like receptor (KIR) by natural killer (NK) cells, which may be pathogenetically involved in …