Comparison of EndoPredict and EPclin with oncotype DX recurrence score for prediction of risk of distant recurrence after endocrine therapy

R Buus, I Sestak, R Kronenwett… - Journal of the …, 2016 - academic.oup.com
Background: Estimating distant recurrence (DR) risk among women with estrogen receptor–
positive (ER+), human epidermal growth factor receptor 2 (HER2)–negative early breast …

[HTML][HTML] Clinical validation of the EndoPredict test in node-positive, chemotherapy-treated ER+/HER2− breast cancer patients: results from the GEICAM 9906 trial

M Martin, JC Brase, L Calvo, K Krappmann… - Breast Cancer …, 2014 - Springer
Introduction EndoPredict (EP) is an RNA-based multigene test that predicts the likelihood of
distant recurrence in patients with estrogen receptor-positive (ER+), human epidermal …

[HTML][HTML] Decentral gene expression analysis for ER+/Her2− breast cancer: results of a proficiency testing program for the EndoPredict assay

C Denkert, R Kronenwett, W Schlake, K Bohmann… - Virchows Archiv, 2012 - Springer
Gene expression profiles provide important information about the biology of breast tumors
and can be used to develop prognostic tests. However, the implementation of quantitative …

Role of heart-type fatty acid-binding protein in early detection of acute myocardial infarction

F Ghani, AHB Wu, L Graff, C Petry… - Clinical …, 2000 - academic.oup.com
Biochemical evidence of acute myocardial infarction (AMI) is delayed by the delay of
appearance of serum cardiac markers in the blood after myocardial injury. Heart-type fatty …

[HTML][HTML] Decentral gene expression analysis: analytical validation of the Endopredict genomic multianalyte breast cancer prognosis test

R Kronenwett, K Bohmann, J Prinzler, BV Sinn, F Haufe… - BMC cancer, 2012 - Springer
Background EndoPredict (EP) is a clinically validated multianalyte gene expression test to
predict distant metastasis in ER-positive, HER2-negative breast cancer treated with …

Quantitative determination of estrogen receptor, progesterone receptor, and HER2 mRNA in formalin-fixed paraffin-embedded tissue—a new option for predictive …

BM Müller, R Kronenwett, G Hennig… - Diagnostic Molecular …, 2011 - journals.lww.com
The development of optimized therapy strategies against malignant tumors is critically
dependent on the assessment of tissue-based biomarkers in routine diagnostic tissue …

[HTML][HTML] Prognostic ability of EndoPredict compared to research-based versions of the PAM50 risk of recurrence (ROR) scores in node-positive, estrogen receptor …

M Martin, JC Brase, A Ruiz, A Prat… - Breast cancer research …, 2016 - Springer
There are several prognostic multigene-based tests for managing breast cancer (BC), but
limited data comparing them in the same cohort. We compared the prognostic performance …

Comparison of the RNA-based EndoPredict multigene test between core biopsies and corresponding surgical breast cancer sections

BM Müller, JC Brase, F Haufe, KE Weber… - Journal of clinical …, 2012 - jcp.bmj.com
Aim This study compared the perfomance of the RNA-based EndoPredict multigene test on
core biopsies and surgical breast cancer specimens and analysed the influence of biopsy …

Gene‐expression signature of tumor recurrence in patients with stage II and III colon cancer treated with 5′ fluoruracil‐based adjuvant chemotherapy

MD Giráldez, JJ Lozano, M Cuatrecasas… - … journal of cancer, 2013 - Wiley Online Library
Although receiving adjuvant chemotherapy after radical surgery, a disappointing proportion
of patients with colorectal cancer will develop tumor recurrence. Probability of relapse is …

[HTML][HTML] From high-throughput microarray-based screening to clinical application: the development of a second generation multigene test for breast cancer prognosis

JC Brase, R Kronenwett, C Petry, C Denkert, M Schmidt - Microarrays, 2013 - mdpi.com
Several multigene tests have been developed for breast cancer patients to predict the
individual risk of recurrence. Most of the first generation tests rely on proliferation-associated …