[HTML][HTML] Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients

D Santini, G Schiavon, B Vincenzi, L Gaeta, F Pantano… - PloS one, 2011 - journals.plos.org
Background Receptor activator of NFkB (RANK), its ligand (RANKL) and the decoy receptor
of RANKL (osteoprotegerin, OPG) play a pivotal role in bone remodeling by regulating …

Endorectal magnetic resonance imaging at 1.5 Tesla to assess local recurrence following radical prostatectomy using T2-weighted and contrast-enhanced imaging

S Cirillo, M Petracchini, L Scotti, T Gallo, A Macera… - European …, 2009 - Springer
To evaluate diagnostic performance of endorectal magnetic resonance (eMR) for
diagnosing local recurrence of prostate cancer (PC) in patients with previous radical …

Association of systemic inflammation index and body mass index with survival in patients with renal cell cancer treated with nivolumab

U De Giorgi, G Procopio, D Giannarelli… - Clinical Cancer …, 2019 - AACR
Purpose: Inflammation indexes and body mass index (BMI) are easily evaluated, predict
survival, and are potentially modifiable. We evaluated the potential association of …

[HTML][HTML] Reorganisation of medical oncology departments during the novel coronavirus disease-19 pandemic: a nationwide Italian survey

A Indini, C Aschele, L Cavanna, M Clerico… - European Journal of …, 2020 - Elsevier
The novel severe acute respiratory syndrome coronavirus-2 pandemic is a global health
problem, which started to affect China by the end of 2019. In Europe, Italy has faced this …

Pazopanib in advanced and platinum-resistant urothelial cancer: an open-label, single group, phase 2 trial

A Necchi, L Mariani, N Zaffaroni, LH Schwartz… - The lancet …, 2012 - thelancet.com
Background The development of new drugs for patients with refractory urothelial cancer is
still an unmet medical need. Preclinical evidence lends support to a rationale for targeting of …

[HTML][HTML] Natural history of non-small-cell lung cancer with bone metastases

D Santini, S Barni, S Intagliata, A Falcone, F Ferraù… - Scientific reports, 2015 - nature.com
We conducted a large, multicenter, retrospective survey aimed to explore the impact of tumor
bone involvement in Non-Small Cell Lung Cancer. Data on clinical-pathology, skeletal …

Treatment of extraspinal painful bone metastases with percutaneous cementoplasty: a prospective study of 50 patients

GC Anselmetti, A Manca, C Ortega, G Grignani… - Cardiovascular and …, 2008 - Springer
The aim of this study was to assess the efficacy of percutaneous cementoplasty (PC) with
polymethylmethacrylate (PMMA) in painful extravertebral lytic bone metastases not …

Clinical outcomes of castration-resistant prostate cancer treatments administered as third or fourth line following failure of docetaxel and other second-line treatment …

O Caffo, U De Giorgi, L Fratino, D Alesini, V Zagonel… - European urology, 2015 - Elsevier
Background The availability of new agents (NAs) active in patients with metastatic castration-
resistant prostate cancer (mCRPC) progressing after docetaxel treatment (abiraterone …

Primary resistance to tyrosine kinase inhibitors in patients with advanced renal cell carcinoma: state-of-the-science

C Porta, R Sabbatini, G Procopio… - Expert review of …, 2012 - Taylor & Francis
Although over 70% of patients with metastatic renal cell carcinoma (RCC) respond to initial
therapy with tyrosine kinase inhibitors (disease control rate 70–80%), approximately 20 …

Surgical resection does not improve survival in patients with renal metastases to the pancreas in the era of tyrosine kinase inhibitors

M Santoni, A Conti, S Partelli, C Porta… - Annals of Surgical …, 2015 - Springer
Background The aim of this study was to compare survival of resected and unresected
patients in a large cohort of patients with metastases to the pancreas from renal cell …