User profiles for "author:D D'Cruz"
 | David D'CruzKing's College London and Guy's Hospital Verified email at kcl.ac.uk Cited by 24119 |
[HTML][HTML] The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome
C Rosário, G Zandman-Goddard, EG Meyron-Holtz… - BMC medicine, 2013 - Springer
Background Over the last few years, accumulating data have implicated a role for ferritin as
a signaling molecule and direct mediator of the immune system. Hyperferritinemia is …
a signaling molecule and direct mediator of the immune system. Hyperferritinemia is …
The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults
Caroline Gordon1, 2, 3, Maame-Boatemaa Amissah-Arthur1, Mary Gayed1, 3, Sue Brown4,
Ian N. Bruce5, 6, David D'Cruz7, Benjamin Empson8, Bridget Griffiths9, David Jayne10, 11 …
Ian N. Bruce5, 6, David D'Cruz7, Benjamin Empson8, Bridget Griffiths9, David Jayne10, 11 …
[HTML][HTML] The role of B lymphocyte stimulator (BLyS) in systemic lupus erythematosus
SLE, a chronic, multisystem autoimmune disorder with a broad range of symptoms, involves
defective B cell selection and elimination of self-reactive B cells. B lymphocyte stimulator …
defective B cell selection and elimination of self-reactive B cells. B lymphocyte stimulator …
[PDF][PDF] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors
Monocytes are effectors of the inflammatory response to microbes. Human CD14+
monocytes specialize in phagocytosis and production of reactive oxygen species and …
monocytes specialize in phagocytosis and production of reactive oxygen species and …
Immunosuppressive therapy in lupus nephritis: the Euro‐Lupus Nephritis Trial, a randomized trial of low‐dose versus high‐dose intravenous cyclophosphamide
FA Houssiau, C Vasconcelos, D D'Cruz… - Arthritis & …, 2002 - Wiley Online Library
Objective Glomerulonephritis is a severe manifestation of systemic lupus erythematosus
(SLE) that is usually treated with an extended course of intravenous (IV) cyclophosphamide …
(SLE) that is usually treated with an extended course of intravenous (IV) cyclophosphamide …
BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group's disease activity index for patients with systemic …
Objective. To devise a more discriminating version of the British Isles Lupus Assessment
Group (BILAG) disease activity index and to show that it is reliable. Methods. A nominal …
Group (BILAG) disease activity index and to show that it is reliable. Methods. A nominal …
The 10-year follow-up data of the Euro-Lupus Nephritis Trial comparing low-dose and high-dose intravenous cyclophosphamide
FA Houssiau, C Vasconcelos, D D'Cruz… - Annals of the …, 2010 - ard.bmj.com
Objective: To update the follow-up of the Euro-Lupus Nephritis Trial (ELNT), a randomised
prospective trial comparing low-dose (LD) and high-dose (HD) intravenous (IV) …
prospective trial comparing low-dose (LD) and high-dose (HD) intravenous (IV) …
Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial
FA Houssiau, D D'Cruz, S Sangle, P Remy… - Annals of the …, 2010 - ard.bmj.com
Background Long-term immunosuppressive treatment does not efficiently prevent relapses
of lupus nephritis (LN). This investigator-initiated randomised trial tested whether …
of lupus nephritis (LN). This investigator-initiated randomised trial tested whether …
The efficacy and safety of abatacept in patients with non–life‐threatening manifestations of systemic lupus erythematosus: results of a twelve‐month, multicenter …
…, R Westhovens, A Chalmers, D D'cruz… - Arthritis & …, 2010 - Wiley Online Library
Objective To evaluate abatacept therapy in patients with non–life‐threatening systemic
lupus erythematosus (SLE) and polyarthritis, discoid lesions, or pleuritis and/or pericarditis …
lupus erythematosus (SLE) and polyarthritis, discoid lesions, or pleuritis and/or pericarditis …
Early response to immunosuppressive therapy predicts good renal outcome in lupus nephritis: lessons from long‐term followup of patients in the Euro‐Lupus Nephritis …
FA Houssiau, C Vasconcelos, D D'Cruz… - Arthritis & …, 2004 - Wiley Online Library
Abstract Objective In the Euro‐Lupus Nephritis Trial (ELNT), 90 patients with lupus nephritis
were randomly assigned to a high‐dose intravenous cyclophosphamide (IV CYC) regimen …
were randomly assigned to a high‐dose intravenous cyclophosphamide (IV CYC) regimen …