Definitive identification of cysteine and glutathione complexes of bismuth by mass spectrometry: assessing the biochemical fate of bismuth pharmaceutical agents

N Burford, MD Eelman, DE Mahony… - Chemical …, 2003 - pubs.rsc.org
Solutions containing BiCl3, bismuth subsalicylate or Bi (NO3) 3 with L-cysteine, DL-
homocysteine, D-methionine or glutathione have been examined by electrospray mass …

Antimicrobial Activities of Synthetic Bismuth Compounds against Clostridium difficile

DE Mahony, S Lim-Morrison, L Bryden… - Antimicrobial agents …, 1999 - Am Soc Microbiol
Clostridium difficile is a major nosocomial pathogen responsible for pseudomembranous
colitis and many cases of antibiotic-associated diarrhea. Because of potential relapse of …

3α-, 7α-And 12α-hydroxysteroid dehydrogenase activities from Clostridium perfringens

IA Macdonald, EC Meier, DE Mahony… - Biochimica et Biophysica …, 1976 - Elsevier
Abstract 25 strains of Clostridium perfringens were screened for hydroxysteroid
dehydrogenase activity; 19 contained NADP-dependent 3α-hydroxysteroid dehydrogenase …

Bile Salt 3α- and 12α-Hydroxysteroid Dehydrogenases from Eubacterium lentum and Related Organisms

IA Macdonald, JF Jellett, DE Mahony… - Applied and …, 1979 - Am Soc Microbiol
Thirty-two strains of Eubacterium lentum and phenotypically similar anaerobic gram-positive
bacilli were screened for intracellular bile salt 3α-and 12α-hydroxysteroid dehydrogenase …

Effect of pH on bile salt degradation by mixed fecal cultures

IA Macdonald, G Singh, DE Mahony, CE Meier - Steroids, 1978 - Elsevier
Stool specimens from 3 healthy volunteers were cultured under anaerobic conditions in
brain heart infusion broth with and without the addition of cholate, deoxycholate or …

A chimeric ribozyme in Clostridium difficile combines features of group I introns and insertion elements

V Braun, M Mehlig, M Moos, M Rupnik… - Molecular …, 2000 - Wiley Online Library
CdISt1, a DNA insertion of 1975 bp, was identified within tcdA‐C34, the enterotoxin gene of
the Clostridium difficile isolate C34. Located in the catalytic domain A1‐C34, CdISt1 …

Stable L-forms of Clostridium perfringens and their growth on glass surfaces

DE Mahony, TI Moore - Canadian Journal of Microbiology, 1976 - cdnsciencepub.com
L-forms of Clostridium perfringens were induced in brain heart infusion broth containing
10% sucrose and 2 units of penicillin. After a few hours of growth, spheroplasts, granules …

12alpha-Hydroxysteroid dehydrogenase from Clostridium group P strain C48-50 ATCC No. 29733: partial purification and characterization.

IA Macdonald, JF Jellett, DE Mahony - Journal of lipid research, 1979 - ASBMB
The growth of Clostridium group P strain C48-50 [an anaerobe that contains 12alpha-
hydroxysteroid dehydrogenase (12alpha-HSDH) in the absence of other dehydrogenases …

Two bacteriophages of Clostridium difficile

DE Mahony, PD Bell… - Journal of clinical …, 1985 - Am Soc Microbiol
Two temperate bacteriophages of differing morphology and host range were isolated by
screening 94 isolates of Clostridium difficile. Phage 41 had a 300-nm flexible tail, whereas …

Vero cell assay for rapid detection of Clostridium perfringens enterotoxin

DE Mahony, E Gilliatt, S Dawson… - Applied and …, 1989 - Am Soc Microbiol
A rapid assay which measured the biological activity of Clostridium perfringens enterotoxin
was developed. The method involved the rapid killing of Vero cells by enterotoxin produced …