The role of T lymphocytes in the pathogenesis of asthma

M Larché, DS Robinson, AB Kay - Journal of Allergy and Clinical …, 2003 - Elsevier
Continuing Medical Education examination CONTINUING MEDICAL EDUCATION
ARTICLECredit can now be obtained, free for a limited time, by reading the following review …

The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences

M Humbert, G Menz, S Ying, CJ Corrigan… - Immunology today, 1999 - cell.com
Intrinsic asthma shows no clinical or serological evidence of IgE-mediated allergy to
common environmental agents. Similar to extrinsic asthma, bronchial biopsies from such …

[HTML][HTML] Tregs and allergic disease

DS Robinson, M Larché… - The Journal of clinical …, 2004 - Am Soc Clin Investig
Allergic diseases such as asthma, rhinitis, and eczema are increasing in prevalence and
affect up to 15% of populations in Westernized countries. The description of Tregs as T cells …

How coping mediates the effect of optimism on distress: a study of women with early stage breast cancer.

CS Carver, C Pozo, SD Harris, V Noriega, MF Scheier… - 1999 - psycnet.apa.org
This reprinted article originally appeared in Journal of Personality and Social Psychology,
65 (2), 375-390 (1993).(The following abstract of the original article appeared in record 1993 …

[HTML][HTML] Predominant TH2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

DS Robinson, Q Hamid, S Ying… - … England Journal of …, 1992 - Mass Medical Soc
Background. In atopic asthma, activated T helper lymphocytes are present in bronchial-
biopsy specimens and bronchoalveolar-lavage (BAL) fluid, and their production of cytokines …

Postmastectomy radiotherapy: clinical practice guidelines of the American Society of Clinical Oncology

A Recht, SB Edge, LJ Solin, DS Robinson… - Journal of clinical …, 2001 - ascopubs.org
OBJECTIVE: To determine indications for the use of postmastectomy radiotherapy (PMRT)
for patients with invasive breast cancer with involved axil-lary lymph nodes or locally …

[HTML][HTML] Reversing the defective induction of IL-10–secreting regulatory T cells in glucocorticoid-resistant asthma patients

E Xystrakis, S Kusumakar, S Boswell… - The Journal of …, 2006 - Am Soc Clin Investig
We previously reported that human CD4+ Tregs secrete high levels of IL-10 when stimulated
in the presence of dexamethasone and calcitriol (vitamin D3). We now show that following …

Relation of CD4+ CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease

EM Ling, T Smith, XD Nguyen, C Pridgeon, M Dallman… - The Lancet, 2004 - thelancet.com
Background Allergic diseases are frequent and rising in prevalence, and result from
activation of T-helper (Th) 2 cells by allergens. CD4+ CD25+ regulatory T cells suppress T …

Eosinophil's role remains uncertain as anti–interleukin-5 only partially depletes numbers in asthmatic airway

PT Flood-Page, AN Menzies-Gow, AB Kay… - American journal of …, 2003 - atsjournals.org
The role of eosinophils as effector cells in asthma pathogenesis has been questioned since
an anti–interleukin (IL)-5 monoclonal antibody (mepolizumab), which depleted blood and …

Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co‐localization of …

S Ying, DS Robinson, Q Meng… - European journal of …, 1997 - Wiley Online Library
Eotaxin is a newly discovered C‐C chemokine which preferentially attracts and activates
eosinophil leukocytes by acting specifically on its receptor CCR3. The airway inflammation …