User profiles for "author:David Schwartz"

David A. Schwartz

Professor of Medicine and Immunology, University of Colorado
Verified email at ucdenver.edu
Cited by 54105

Toll-like receptors in the pathogenesis of human disease

DN Cook, DS Pisetsky, DA Schwartz - Nature immunology, 2004 - nature.com
Members of the Toll-like receptor (TLR) family are key regulators of both innate and adaptive
immune responses. The function of TLRs in various human diseases has been investigated …

An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and …

DA Schwartz - Archives of pathology & laboratory medicine, 2020 - meridian.allenpress.com
The emergence of a novel coronavirus, termed SARS-CoV-2, and the potentially life-
threatening respiratory disease that it can produce, COVID-19, has rapidly spread across the …

Human microsporidial infections

R Weber, RT Bryan, DA Schwartz… - Clinical microbiology …, 1994 - Am Soc Microbiol
Microsporidia are obligate intracellular spore-forming protozoal parasites belonging to the
phylum Microspora. Their host range is extensive, including most invertebrates and all …

The B73 maize genome: complexity, diversity, and dynamics

PS Schnable, D Ware, RS Fulton, JC Stein, F Wei… - science, 2009 - science.org
We report an improved draft nucleotide sequence of the 2.3-gigabase genome of maize, an
important crop plant and model for biological research. Over 32,000 genes were predicted …

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

DC Schwartz, CR Cantor - cell, 1984 - cell.com
A new type of gel electrophoresis separates DNA molecules up to 2000 kb with resolutions
exceeding the logarithmic molecular weight dependence of conventional electrophoresis …

Mapping and sequencing of structural variation from eight human genomes

JM Kidd, GM Cooper, WF Donahue, HS Hayden… - Nature, 2008 - nature.com
Genetic variation among individual humans occurs on many different scales, ranging from
gross alterations in the human karyotype to single nucleotide changes. Here we explore …

The Genome of the Diatom Thalassiosira Pseudonana: Ecology, Evolution, and Metabolism

EV Armbrust, JA Berges, C Bowler, BR Green… - Science, 2004 - science.org
Diatoms are unicellular algae with plastids acquired by secondary endosymbiosis. They are
responsible for∼ 20% of global carbon fixation. We report the 34 million–base pair draft …

The Genome of the Kinetoplastid Parasite, Leishmania major

AC Ivens, CS Peacock, EA Worthey, L Murphy… - Science, 2005 - science.org
Leishmania species cause a spectrum of human diseases in tropical and subtropical
regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase …

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

NC Arbour, E Lorenz, BC Schutte, J Zabner, JN Kline… - Nature …, 2000 - nature.com
There is much variability between individuals in the response to inhaled toxins, but it is not
known why certain people develop disease when challenged with environmental agents …

Genome sequence of enterohaemorrhagic Escherichia coli O157:H7

NT Perna, G Plunkett III, V Burland, B Mau, JD Glasner… - Nature, 2001 - nature.com
The bacterium Escherichia coli O157: H7 is a worldwide threat to public health and has
been implicated in many outbreaks of haemorrhagic colitis, some of which included fatalities …